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Full-Text Articles in Medicine and Health Sciences

Patterns Of Infant Mortality In The Upper St. John Valley French Population: 1791-1838, Marcella H. Sorg, Beatrice C. Craig Feb 1983

Patterns Of Infant Mortality In The Upper St. John Valley French Population: 1791-1838, Marcella H. Sorg, Beatrice C. Craig

Anthropology Faculty Scholarship

The purpose of this paper is to provide a descriptive analysis of infant mortality patterns in a pre-industrial North American population, the Madawaska French of the upper St. John Valley. A synchronic approach was taken in examining a series of 320 infant deaths identified through family reconstitution. The infant mortality rate for the series is 132 per 1000, low compared to other pre-industrial populations. The large average completed family size of 11.34 is associated with short birth intervals averaging 21.9 months. Women who experience infant mortality were found to have significantly larger completed families that those who did not. Infant …


Comparison Of Intermediate-Dose Methotrexate With Cranial Irradiation For The Post-Induction Treatment Of Acute Lymphocytic Leukemia In Children, Arnold I. Freeman , M.D., Vivian Weinberg, Martin L. Brecher , M.D., Barbara Jones , M.D., Arvin S. Glicksman , M.D., Lucius F. Sinks , M.D., Marise Weil , M.D., Hansjuerg Pleuss , M.D., Juliet Hananian , M.D., E. Omer Burgert , Jr., M.D., Gerald S. Gilchrist , M.D., Thomas Necheles , M.D., Michael Harris , M.D., Faith Kung , M.D., Richard B. Patterson , M.D., Harold Maurer , M.D., Brigid Leventhal , M.D., Louise Chevalier , M.D., Edwin Forman , M.D., James F. Holland , M.D. Jan 1983

Comparison Of Intermediate-Dose Methotrexate With Cranial Irradiation For The Post-Induction Treatment Of Acute Lymphocytic Leukemia In Children, Arnold I. Freeman , M.D., Vivian Weinberg, Martin L. Brecher , M.D., Barbara Jones , M.D., Arvin S. Glicksman , M.D., Lucius F. Sinks , M.D., Marise Weil , M.D., Hansjuerg Pleuss , M.D., Juliet Hananian , M.D., E. Omer Burgert , Jr., M.D., Gerald S. Gilchrist , M.D., Thomas Necheles , M.D., Michael Harris , M.D., Faith Kung , M.D., Richard B. Patterson , M.D., Harold Maurer , M.D., Brigid Leventhal , M.D., Louise Chevalier , M.D., Edwin Forman , M.D., James F. Holland , M.D.

Pediatrics Publications

Abstract

We compared two regimens with respect to their ability to prolong disease-free survival in 506 children and adolescents with acute lymphocytic leukemia. All responders to induction therapy were randomized to treatment with 2400 rad of cranial irradiation plus intrathecal methotrexate or to treatment with intermediate-dose methotrexate plus intrathecal methotrexate, as prophylaxis for involvement of the central nervous system and other "sanctuary" areas. Patients were then treated with a standard maintenance regimen. Complete responders were stratified into either standard-risk or increased-risk groups on the basis of age and white-cell count at presentation.

Among patients with standard risk, hematologic relapses occurred …


Pediatrics, Susan P. Dunkley Jan 1983

Pediatrics, Susan P. Dunkley

UND Departmental Histories

This departmental history was written on the occasion of the UND Centennial in 1983.