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Full-Text Articles in Medicine and Health Sciences
Evidence Of Chikungunya Virus Disease In Pakistan Since 2015 With Patients Demonstrating Involvement Of The Central Nervous System, Kelli L. Barr, Erum Khan, Joveria Farooqi, Kehkashan Imtiaz, Dhani Prakoso, Faisal Malik, John A. Lednicky, Maureen T. Long
Evidence Of Chikungunya Virus Disease In Pakistan Since 2015 With Patients Demonstrating Involvement Of The Central Nervous System, Kelli L. Barr, Erum Khan, Joveria Farooqi, Kehkashan Imtiaz, Dhani Prakoso, Faisal Malik, John A. Lednicky, Maureen T. Long
Department of Pathology and Laboratory Medicine
Several arboviruses are endemic to and co-circulate in Pakistan. In recent years, Pakistan has observed a rise in arboviral infections. A cross-sectional study for arboviral diseases, which included screening for Chikungunya virus (CHIKV), was initiated in 2015 to determine which pathogens were causing disease in patients presenting to health care services. Exposure to CHIKV was verified via detection of viral nucleic acids or virus-specific IgM with virus-specific neutralizing antibodies. Out of 997 enrolled patients presenting with clinical features suggestive of arboviral disease, 102 patients were positive for CHIKV IgM antibodies and 60 patients were positive for CHIKV nucleic acids or …
Human West Nile Virus Disease Outbreak In Pakistan, 2015–2016, E. Khan, Kelli L. Barr, Joveria Farooqi, Dhani Prakoso, Alizae Abbas, Zain Y. Khan, Shanze Ashi, Kehkashan Imtiaz, Z Aziz, Faisal Malik
Human West Nile Virus Disease Outbreak In Pakistan, 2015–2016, E. Khan, Kelli L. Barr, Joveria Farooqi, Dhani Prakoso, Alizae Abbas, Zain Y. Khan, Shanze Ashi, Kehkashan Imtiaz, Z Aziz, Faisal Malik
Department of Pathology and Laboratory Medicine
Like most of the world, Pakistan has seen an increase in mosquito-transmitted diseases in recent years. The magnitude and distribution of these diseases are poorly understood as Pakistan does not have a nation-wide system for reporting disease. A cross-sectional study to determine which flaviviruses were causing of arboviral disease in Pakistan was instituted. West Nile virus (WNV) is a cause of seasonal fever with neurotropic findings in countries that share borders with Pakistan. Here, we describe the active and persistent circulation of WNV in humans in the southern region of Pakistan. This is the first report of WNV causing neurological …