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Pathology

Aga Khan University

Section of Haematology/Oncology

2021

HLA‐DR positivity

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The Curious Case Of Hla-Dr-Positive Apl, Kanta Devi, Natasha Bahadur Ali Dec 2021

The Curious Case Of Hla-Dr-Positive Apl, Kanta Devi, Natasha Bahadur Ali

Section of Haematology/Oncology

The triad of weak/absent CD34, negative HLA-DR expression, and positivity to CD117 is pathognomonic for the diagnosis of acute promyelocytic leukemia. However, in rare cases, strong positivity to HLD-DR and CD34 may be noted.

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