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Full-Text Articles in Medicine and Health Sciences

Recommendations For Head And Neck Surgical Oncology Practice In A Setting Of Acute Severe Resource Constraint During The Covid-19 Pandemic: An International Consensus., H Mehanna, Jc Hardman, Ja Shenson, Ak Abou-Foul, Mc Topf, M Alfalasi, Jyk Chan, P Chaturvedi, D Kraus, C R. Leemans, +15 Additional Authors Jan 2020

Recommendations For Head And Neck Surgical Oncology Practice In A Setting Of Acute Severe Resource Constraint During The Covid-19 Pandemic: An International Consensus., H Mehanna, Jc Hardman, Ja Shenson, Ak Abou-Foul, Mc Topf, M Alfalasi, Jyk Chan, P Chaturvedi, D Kraus, C R. Leemans, +15 Additional Authors

Journal Articles

No abstract provided.


Autoimmune Inner Ear Disease Patient-Associated 28-Kda Proinflammatory Il-1 Beta Fragment Results From Caspase-7 Mediated Cleavage In Vitro, S. Pathak, A. Vambutas Jan 2020

Autoimmune Inner Ear Disease Patient-Associated 28-Kda Proinflammatory Il-1 Beta Fragment Results From Caspase-7 Mediated Cleavage In Vitro, S. Pathak, A. Vambutas

Journal Articles

No abstract provided.


An Oxygen-Rich Atmosphere Or Systemic Fluoxetine Extend The Time To Respiratory Arrest In A Rat Model Of Obstructive Apnea, S. Mooney, R. Kollmar, R. Gurevich, J. Tromblee, A. Banerjee, K. Sundaram, J. B. Silverman, M. Stewart Jan 2020

An Oxygen-Rich Atmosphere Or Systemic Fluoxetine Extend The Time To Respiratory Arrest In A Rat Model Of Obstructive Apnea, S. Mooney, R. Kollmar, R. Gurevich, J. Tromblee, A. Banerjee, K. Sundaram, J. B. Silverman, M. Stewart

Journal Articles

© 2019 Elsevier Inc. Audiogenic seizure-prone mice can be protected from seizure-associated death by exposure to an oxygen atmosphere or treatment with selective serotonergic reuptake inhibitors (SSRIs). We have shown previously in a rat model that epileptic seizure activity can spread through brainstem areas to cause sufficient laryngospasm for obstructive apnea and that the period of seizure-associated obstructive apnea can last long enough for respiratory arrest to occur. We hypothesized that both the oxygen-rich atmosphere and SSRIs function by prolonging the time to respiratory arrest, thus ensuring that seizure activity stops before the point of respiratory arrest to allow recovery …


A Near-Infrared Probe For Non-Invasively Monitoring Cerebrospinal Fluid Flow By F-18-Positron Emitting Tomography And Fluorescence, H. Guo, H. Kommidi, C. C. Lekaye, J. Koutcher, M. S. Judenhofer, S. R. Cherry, A. P. Wu, O. Akin, M. M. Souweidane, R. Ting, +2 Additional Authors Jan 2020

A Near-Infrared Probe For Non-Invasively Monitoring Cerebrospinal Fluid Flow By F-18-Positron Emitting Tomography And Fluorescence, H. Guo, H. Kommidi, C. C. Lekaye, J. Koutcher, M. S. Judenhofer, S. R. Cherry, A. P. Wu, O. Akin, M. M. Souweidane, R. Ting, +2 Additional Authors

Journal Articles

No abstract provided.


A New Office-Based Procedure For Treatment Of Snoring: The S.I.Le.N.C.E. Study., M. Friedman, M. B. Gillespie, F. A. Shabdiz, D. H. Hiltzik, T. A. Meyer, J. Ahn, P. J. Catalano, N. J. Joseph Jan 2020

A New Office-Based Procedure For Treatment Of Snoring: The S.I.Le.N.C.E. Study., M. Friedman, M. B. Gillespie, F. A. Shabdiz, D. H. Hiltzik, T. A. Meyer, J. Ahn, P. J. Catalano, N. J. Joseph

Journal Articles

Objective:Demonstrate the safety and effectiveness of palatal foreshortening and stiffening in reducing snoring severity in nonobstructive sleep apnea (non-OSA) patients complaining of chronic disruptive snoring. Methods:In a US-based 8-center, open-label, prospective, single-arm cohort study, 52 consenting adults with chronic disruptive snoring (snoring impacting a patient's life and causing patient or bed partner to seek medical intervention) were treated via office-based placement of resorbable, bidirectional, barbed suture implants into the soft palate under local anesthesia. Prior to intervention, home sleep tests (HSTs) were performed to rule out OSA and to document snoring noise level. Both subject and their bed/sleep partners (also …


How Can We Improve Antidepressant Adherence In The Management Of Depression? A Targeted Review And 10 Clinical Recommendations., M. Solmi, A. Miola, G. Croatto, G. Pigato, A. Favaro, M. Fornaro, M. Berk, L. Smith, C. U. Correll, A. F. Carvalho, +2 Additional Authors Jan 2020

How Can We Improve Antidepressant Adherence In The Management Of Depression? A Targeted Review And 10 Clinical Recommendations., M. Solmi, A. Miola, G. Croatto, G. Pigato, A. Favaro, M. Fornaro, M. Berk, L. Smith, C. U. Correll, A. F. Carvalho, +2 Additional Authors

Journal Articles

Adherence to antidepressants is crucial for optimal treatment outcomes when treating depressive disorders. However, poor adherence is common among patients prescribed antidepressants. This targeted review summarizes the main factors associated with poor adherence, interventions that promote antidepressant adherence, pharmacological aspects related to antidepressant adherence, and formulates 10 clinical recommendations to optimize antidepressant adherence. Patient-related factors associated with antidepressant non-adherence include younger age, psychiatric and medical comorbidities, cognitive impairment, and substance use disorders. Prescriber behavior-related factors include neglecting medical and family histories, selecting poorly tolerated antidepressants, or complex antidepressant regimens. Multi-disciplinary interventions targeting both patient and prescriber, aimed at improving antidepressant …


Consortium Of Otolaryngology Journal Editors: Collegiality And Contributions, R. T. Sataloff, R. Chandra, E. W. Fisher, D. Goldenberg, E. Y. Hanna, J. Johnson, D. W. Kennedy, D. H. Kraus, J. H. Krouse, D. B. Welling, +12 Additional Authors Jan 2020

Consortium Of Otolaryngology Journal Editors: Collegiality And Contributions, R. T. Sataloff, R. Chandra, E. W. Fisher, D. Goldenberg, E. Y. Hanna, J. Johnson, D. W. Kennedy, D. H. Kraus, J. H. Krouse, D. B. Welling, +12 Additional Authors

Journal Articles

No abstract provided.


Seizures Induce Obstructive Apnea In Dba/2j Audiogenic Seizure-Prone Mice: Lifesaving Impact Of Tracheal Implants, R. Irizarry, D. Sukato, R. Kollmar, S. Schild, J. Silverman, K. Sundaram, S. Stephenson, M. Stewart Jan 2020

Seizures Induce Obstructive Apnea In Dba/2j Audiogenic Seizure-Prone Mice: Lifesaving Impact Of Tracheal Implants, R. Irizarry, D. Sukato, R. Kollmar, S. Schild, J. Silverman, K. Sundaram, S. Stephenson, M. Stewart

Journal Articles

Wiley Periodicals, Inc. © 2020 International League Against Epilepsy The mechanism(s) for sudden death in epilepsy (SUDEP) remain(s) unknown, but seizure spread to brainstem areas serving autonomic and respiratory function is critical. In a rat model, we established a mechanism for SUDEP that involves seizure-induced laryngospasm and obstructive apnea lasting until respiratory arrest. We hypothesized that DBA/2J mice, which display lethal audiogenic seizures, would be protected from death by implanting a tracheal T-tube as a surrogate airway. In a 2 × 2 design, mice were implanted with either open or closed tracheal T-tubes and treated with either low-dose ketamine/xylazine to …