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Full-Text Articles in Medicine and Health Sciences
The Effect Of Simulations On Nursing Students’ Ethical Reasoning Confidence In Disasters: A Pilot Study, Sara E. Greco
The Effect Of Simulations On Nursing Students’ Ethical Reasoning Confidence In Disasters: A Pilot Study, Sara E. Greco
Senior Honors Projects, 2010-2019
This study measured the effect of a disaster nursing simulation and debriefing session on senior BSN students’ perceived ethical reasoning confidence and their belief in the importance of ethical reasoning. Using a quasi-experimental design, this study compared participants’ responses before and after the interventional activities using the Survey of Ethical Reasoning. Post-test results demonstrated an increase in students’ perceived ethical reasoning confidence, perceived importance of ethical reasoning, and utilization of James Madison University’s Eight Key Questions Ethical Reasoning Framework.
Investigating The Use Of Chloroquine As Antineoplastic Therapy, Catherine E. Herron, Alexandra E. Mason
Investigating The Use Of Chloroquine As Antineoplastic Therapy, Catherine E. Herron, Alexandra E. Mason
Senior Honors Projects, 2010-2019
Chloroquine (CQ) is an oral lysosomotropic agent routinely used as an anti-malarial drug (Espina & Liotta, 2013). In recent years, it has been discovered that CQ also possesses anticancer effects, potentially due to the drug’s inhibition of autophagy (Kimura, Takabatake, Takahashi, & Isaka, 2012). Autophagy is a normal cellular pathway that allows for the degradation of cytoplasmic contents. In cancer cells autophagy can also serve as a pro-survival pathway under stressful metabolic conditions, ultimately promoting the survival of malignant cells (Sui et al., 2013). Therefore, in recent years CQ has been speculated as a potential antineoplastic therapy. When administered in …