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Effect Of Low-Intensity Long-Duration Ultrasound On The Symptomatic Relief Of Knee Osteoarthritis: A Randomized, Placebo-Controlled Double-Blind Study, Dominic Klyve, Ralph Ortiz, Davie O. Draper, Thomas M. Best
Effect Of Low-Intensity Long-Duration Ultrasound On The Symptomatic Relief Of Knee Osteoarthritis: A Randomized, Placebo-Controlled Double-Blind Study, Dominic Klyve, Ralph Ortiz, Davie O. Draper, Thomas M. Best
Mathematics Faculty Scholarship
Background: Wearable long-duration low-intensity ultrasound is an emerging non-invasive and non-narcotic therapy for the daily treatment of musculoskeletal pain. The aim of this randomized, double-blind, placebo-controlled study was to examine whether long-duration low-intensity ultrasound was effective in treating pain and improving function in patients with knee osteoarthritis. Methods: Ninety patients with moderate to severe knee pain and radiographically confirmed knee osteoarthritis (Kellgren-Lawrence grade I/II) were randomized for treatment with active (n = 55) or placebo (n = 35) devices applied daily to the treated knee. Investigators and subjects were blinded to treatment groups. Ultrasound (3 MHz, 0.132 W/cm2, 1.3 W) …