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Sensory Hypoinnervation In Club Foot, M Ahmed, N Ahmed, K. M. Khan, Masood Umer, H. Rashid,, Pervaiz Hashmi
Sensory Hypoinnervation In Club Foot, M Ahmed, N Ahmed, K. M. Khan, Masood Umer, H. Rashid,, Pervaiz Hashmi
Department of Surgery
Abstract
We have compared the density of nerve fibres in the synovium in club foot with that of specimens obtained from the synovium of the hip at operations for developmental dysplasia. The study focused on the sensory neuropeptides substance P; calcitonin gene-related peptide; protein gene product 9.5, a general marker for mature peripheral nerve fibres; and growth associated protein 43, a neuronal marker for new or regenerating nerve fibres. In order to establish whether there might be any inherent difference we analysed the density of calcitonin gene-related peptide-positive nerve fibres in the hip and ankle joints in young rats. Semi-quantitative …