Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 3 of 3
Full-Text Articles in Medicine and Health Sciences
Response Dynamics Of Retinal Ganglion And Early Visual Cortical Cells To Simulated Optical Blur, Michael Lance Risner
Response Dynamics Of Retinal Ganglion And Early Visual Cortical Cells To Simulated Optical Blur, Michael Lance Risner
All ETDs from UAB
Visual neurons are highly sensitive to changes in luminance around the mean level of light. The effects of changes in luminance contrast on the responses of retinal ganglion cells (RGCs) and V1 neurons have been extensively studied. Sharp transitions in luminance signify edges, which are key features in the visual environment. However, edges are rarely sharp and may be blurred. Edges are generally blurred because eyes have a restricted depth of field, sources of light are rarely point sources, edges are typically smooth, and rapid motion induces blur. The purpose of this research was to understand how RGCs and V1 …
Overexpression Of Garp2 Increases Phototransduction Gain., Shanta Sarfare
Overexpression Of Garp2 Increases Phototransduction Gain., Shanta Sarfare
All ETDs from UAB
The cGMP-gated cation channel (CNG) in the rod photoreceptors is an essential component of phototransduction, and may have a role in maintaining structural integrity of the rod outer segment (ROS). The ß-subunit of the CNG channel (CNGB1) in the rod photoreceptors is comprised of an N-terminal glutamic acid-rich region (GARP') and a C-terminal channel-like region. Additionally, two soluble proteins GARP1 and GARP2 are alternatively spliced from the CNGB1 gene. Although GARPs are known to interact with other proteins in the rod photoreceptors, their role is currently unknown. To determine the role of GARP2 in the rod photoreceptors, we generated transgenic …
Exploration Of The Crosslinks Between Saccadic And Vergence Eye Movement Pathways Using Motor And Visual Perturbations, Kevin Paul Schultz
Exploration Of The Crosslinks Between Saccadic And Vergence Eye Movement Pathways Using Motor And Visual Perturbations, Kevin Paul Schultz
All ETDs from UAB
Disconjugate movements of the two eyes can either be the result of unequal left-eye and right-eye commands or the sum of binocular conjugate and vergence commands, which symmetrically affect the two eyes in equal and opposite directions, respectively. Of particular relevance is the nature of the intra-saccadic vergence acceleration observed during combined vergence-saccade responses. This effect may be the result of asymmetric left-eye and right-eye saccades or a saccadic-driven acceleration of the vergence signal. The latter is consistent with the OPN Multiply model, in which the saccadic pause of the omnipause neurons (OPNs) elicits the vergence enhancement. We verified, in …