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Full-Text Articles in Medicine and Health Sciences
High Dietary Level Of Synthetic Vitamin E On Lipid Peroxidation, Membrane Fatty Acid Composition And Cytotoxicity In Breast Cancer Xenograft And In Mouse Host Tissue, Ivan L. Cameron, Jesus Munoz, Christopher J. Barnes, W. Elaine Hardman
High Dietary Level Of Synthetic Vitamin E On Lipid Peroxidation, Membrane Fatty Acid Composition And Cytotoxicity In Breast Cancer Xenograft And In Mouse Host Tissue, Ivan L. Cameron, Jesus Munoz, Christopher J. Barnes, W. Elaine Hardman
Biochemistry and Microbiology
Background
d-α-tocopherol is a naturally occurring form of vitamin E not previously known to have antitumor activity. Synthetic vitamin E (sE) is a commonly used dietary supplement consisting of a mixture of d-α-tocopherol and 7 equimolar stereoisomers. To test for antilipid peroxidation and for antitumor activity of sE supplementation, two groups of nude mice bearing a MDA-MB 231 human breast cancer tumor were fed an AIN-76 diet, one with and one without an additional 2000 IU/kg dry food (equivalent to 900 mg of all-rac-α-tocopherol or sE). This provided an intake of about 200 mg/kg body weight per day. The mice …
Validation Of The Lognormal Model For Prediction Of Long-Term Survival Rates From Short-Term Follow Up Data In Stages Iii And Iv Breast Cancer, P. Tai, E. Yu, D. Skarsgard, J. Tonita
Validation Of The Lognormal Model For Prediction Of Long-Term Survival Rates From Short-Term Follow Up Data In Stages Iii And Iv Breast Cancer, P. Tai, E. Yu, D. Skarsgard, J. Tonita
Edward Yu
No abstract provided.