Open Access. Powered by Scholars. Published by Universities.®
- Keyword
-
- AIDS (1)
- Autoantibody (1)
- Autoimmunity (1)
- Cancer (1)
- Carcinoma, Hepatocellular (1)
-
- Causal effect (1)
- Cytokine (1)
- Disease Progression (1)
- Ethanol (1)
- Hepacivirus (1)
- Hepatitis C, Chronic (1)
- Humans (1)
- Immune Tolerance (1)
- Immunity, Innate (1)
- Liver (1)
- Liver Diseases, Alcoholic (1)
- Liver Neoplasms (1)
- Methodology (1)
- Neoplasms (1)
- Proportional hazards model (1)
- Prostate cancer (1)
- Time-dependent confounder (1)
- Treatment by indication (1)
- Publication
Articles 1 - 3 of 3
Full-Text Articles in Medicine and Health Sciences
Pathogenic Interactions Between Alcohol And Hepatitis C, Gyongyi Szabo
Pathogenic Interactions Between Alcohol And Hepatitis C, Gyongyi Szabo
Gyongyi Szabo
Alcohol is the most commonly abused substance in the United States, and alcohol abuse leads to alcoholic liver disease, a long recognized major public health concern. The high prevalence of chronic hepatitis C virus (HCV) infection, along with the clinical observation that HCV infection is common in alcoholic patients presenting with liver disease, has directed attention to the interaction between alcohol and HCV infection. Clinical studies have identified alcohol use as an independent risk factor for progression of fibrosis in chronic HCV infection. Experimental evidence suggests additive inhibitory effects between HCV and alcohol on antiviral immune responses. In addition, specific …
A Review Of Autoimmune Diseases Associated With Cancer, Patricia Tai, Edward Yu, Kurian Joseph, Thomas Miale
A Review Of Autoimmune Diseases Associated With Cancer, Patricia Tai, Edward Yu, Kurian Joseph, Thomas Miale
Edward Yu
The focus of this review is on the relationships between autoimmune diseases and cancer from two closely related perspectives: 1.Those autoimmune diseases which are often associated with malignancies. 2.Those prevalent cancers which may increase the risks of developing autoimmune disorders. The review concludes with a brief discussion of some selected innovative approaches to cancer immunotherapy.
The Effect Of Salvage Therapy On Survival In A Longitudinal Study With Treatment By Indication, Edward Kennedy, Jeremy Taylor, Douglas Schaubel, Scott Williams
The Effect Of Salvage Therapy On Survival In A Longitudinal Study With Treatment By Indication, Edward Kennedy, Jeremy Taylor, Douglas Schaubel, Scott Williams
Edward H. Kennedy
We consider using observational data to estimate the effect of a treatment on disease recurrence, when the decision to initiate treatment is based on longitudinal factors associated with the risk of recurrence. The effect of salvage androgen deprivation therapy (SADT) on the risk of recurrence of prostate cancer is inadequately described by the existing literature. Furthermore, standard Cox regression yields biased estimates of the effect of SADT, since it is necessary to adjust for prostate-specific antigen (PSA), which is a time-dependent confounder and an intermediate variable. In this paper, we describe and compare two methods which appropriately adjust for PSA …