Open Access. Powered by Scholars. Published by Universities.®
- Keyword
-
- Carcinoma, Hepatocellular (2)
- Ethanol (2)
- Immunity, Innate (2)
- Animals (1)
- CD4-Positive T-Lymphocytes (1)
-
- Disease Progression (1)
- Female (1)
- Forkhead Transcription Factors (1)
- Hepacivirus (1)
- Hepatitis B, Chronic (1)
- Hepatitis C (1)
- Hepatitis C, Chronic (1)
- Immune Tolerance (1)
- Killer Cells, Natural (1)
- Liver (1)
- Liver Diseases, Alcoholic (1)
- Male (1)
- MicroRNAs (1)
- Oxidative Stress (1)
- T-Lymphocytes, Cytotoxic (1)
- Virus Replication (1)
Articles 1 - 3 of 3
Full-Text Articles in Medicine and Health Sciences
Alcohol And Hcv: Implications For Liver Cancer, Gyongyi Szabo, Banishree Saha, Terence Bukong
Alcohol And Hcv: Implications For Liver Cancer, Gyongyi Szabo, Banishree Saha, Terence Bukong
Gyongyi Szabo
Liver cancers are one of the deadliest known malignancies which are increasingly becoming a major public health problem in both developed and developing countries. Overwhelming evidence suggests a strong role of infection with hepatitis B and C virus (HBV and HCV), alcohol abuse, as well as metabolic diseases such as obesity and diabetes either individually or synergistically to cause or exacerbate the development of liver cancers. Although numerous etiologic mechanisms for liver cancer development have been advanced and well characterized, the lack of definite curative treatments means that gaps in knowledge still exist in identifying key molecular mechanisms and pathways …
Another Armed Cd4(+) T Cell Ready To Battle Hepatocellular Carcinoma, Roniel Cabrera, Gyongyi Szabo
Another Armed Cd4(+) T Cell Ready To Battle Hepatocellular Carcinoma, Roniel Cabrera, Gyongyi Szabo
Gyongyi Szabo
No abstract provided.
Pathogenic Interactions Between Alcohol And Hepatitis C, Gyongyi Szabo
Pathogenic Interactions Between Alcohol And Hepatitis C, Gyongyi Szabo
Gyongyi Szabo
Alcohol is the most commonly abused substance in the United States, and alcohol abuse leads to alcoholic liver disease, a long recognized major public health concern. The high prevalence of chronic hepatitis C virus (HCV) infection, along with the clinical observation that HCV infection is common in alcoholic patients presenting with liver disease, has directed attention to the interaction between alcohol and HCV infection. Clinical studies have identified alcohol use as an independent risk factor for progression of fibrosis in chronic HCV infection. Experimental evidence suggests additive inhibitory effects between HCV and alcohol on antiviral immune responses. In addition, specific …