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Full-Text Articles in Medicine and Health Sciences
Practicing What We Preach? A Study Of The Implementation Of Exemplary Midwifery Process In Clinical Education, Ginette Lange
Practicing What We Preach? A Study Of The Implementation Of Exemplary Midwifery Process In Clinical Education, Ginette Lange
Seton Hall University Dissertations and Theses (ETDs)
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Placental Peroxisome Proliferator-Activated Receptor Gamma And Leptin Receptor In Human Pregnancy, Gwyneth H. Gladstones
Placental Peroxisome Proliferator-Activated Receptor Gamma And Leptin Receptor In Human Pregnancy, Gwyneth H. Gladstones
Theses : Honours
Leptin is a 16kDa peptide hormone that has recently been implicated in human reproductive processes. Like other hormones, leptin exerts its influence through its receptor. Of the three major isoforms of the receptor (OB-Ra, OB-Rb, and 0B-Re), OB-Ra (the dominant short form) has been implicated in transport processes within rat and human placentas, suggesting a role for it in implantation and pregnancy maintenance. The peroxisome proliferator-activated receptors (PPARs) are ligand-dependent transcription factors that are a subfamily of nuclear hormone receptors. PPARs form heterodimers with another nuclear hormone receptor, RXRα, before binding to PPAR response elements (PPREs). Recently PPARϒ/RXRα heterodimers have …