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Full-Text Articles in Medicine and Health Sciences

Improving Prenatal Education In A Health Center: A Pilot Study, Marcy Keddy Boucher, Hugh Silk, Judith A. Savageau, Katharine C. Barnard, Mary Flynn Dec 2011

Improving Prenatal Education In A Health Center: A Pilot Study, Marcy Keddy Boucher, Hugh Silk, Judith A. Savageau, Katharine C. Barnard, Mary Flynn

Judith A. Savageau

Background: Currently, the timing and variety of health education topics that are covered during prenatal visits are decided upon by the individual physician caring for the patient. Consequently, some patients do not gain exposure to important subject matter that could potentially improve their satisfaction and pregnancy outcomes. Previously reported studies have found evidence that improved patient education may increase rates of breastfeeding (as well as duration), seat belt use during pregnancy, and decrease preterm low birth weight infants. In addition, one study has shown that when prenatal visits are targeted to specific objectives, the number of prenatal visits can …


Advancing Stage Of Female Reproductive Life Associated With Bipolar Illness Exacerbation, Wendy K. Marsh, Terence Ketter, Sybil L. Crawford, Julia V. Johnson, Anthony J. Rothschild Sep 2011

Advancing Stage Of Female Reproductive Life Associated With Bipolar Illness Exacerbation, Wendy K. Marsh, Terence Ketter, Sybil L. Crawford, Julia V. Johnson, Anthony J. Rothschild

Sybil L. Crawford

Introduction: Perimenopause confers an increased risk of depression in the general population, yet bipolar disorder mood course remains unknown. Methods: Clinic visits in 519 premenopausal, 116 perimenopausal including 13 women transitioning from peri- to postmenopause, and 133 postmenopausal women with bipolar disorder who received naturalistic treatment in the multisite STEP-Bipolar Disorder study over 19.8 +/- 15.5 months were analyzed for mood state. Results: Advancing female reproductive stage was associated with significant decline in mood elevation; significant decline in euthymia; no significant difference in major depression; and symptomatic significant increase. Conclusions: Advancing stage of female reproductive life was associated with bipolar …


A Dominant Loss-Of-Function Gja1 (Cx43) Mutant Impairs Parturition In The Mouse, Dan Tong, Xuerong Lu, Hong-Xing Wang, Isabelle Plante, Ed Lui, Dale Laird, Donglin Bai, Gerald Kidder May 2011

A Dominant Loss-Of-Function Gja1 (Cx43) Mutant Impairs Parturition In The Mouse, Dan Tong, Xuerong Lu, Hong-Xing Wang, Isabelle Plante, Ed Lui, Dale Laird, Donglin Bai, Gerald Kidder

Edmund M. K. Lui

Expression of GJA1 (commonly known as connexin43 or Cx43), a major myometrial gap junction protein, is upregulated before the onset of delivery, suggesting an essential role for Cx43-mediated gap junctional intercellular communication (GJIC) in normal uterine contraction during parturition. To determine how a disease-linked Cx43 mutation affects myometrial function, we studied a mutant mouse model carrying an autosomal dominant mutation (Gja1Jrt) in the gene encoding Cx43 that displays features of the human genetic disease oculodentodigital dysplasia. We found that Cx43 level, specifically the phosphorylated species of the protein, is significantly reduced in the myometrium of the mutant mice (Gja1Jrt/+), as …


Knowledge Of Breast Disease And Breast Pathology In The Obstetrics And Gynecology Resident, Andra K. Cicero Feb 2011

Knowledge Of Breast Disease And Breast Pathology In The Obstetrics And Gynecology Resident, Andra K. Cicero

Andra Cicero, DO, FACOG

No abstract provided.


Optimal Time On Haart For Prevention Of Mother-To-Child Transmission Of Hiv, Carla J. Chibwesa, Mark J. Giganti, Nande Putta, Namwinga T. Chintu, Jessica Mulindwa, Benjamin J. Dorton, Benjamin H. Chi, Jeffrey S. A. Stringer, Elizabeth M. Stringer Dec 2010

Optimal Time On Haart For Prevention Of Mother-To-Child Transmission Of Hiv, Carla J. Chibwesa, Mark J. Giganti, Nande Putta, Namwinga T. Chintu, Jessica Mulindwa, Benjamin J. Dorton, Benjamin H. Chi, Jeffrey S. A. Stringer, Elizabeth M. Stringer

Benjamin J. Dorton. MD

OBJECTIVES:
To determine the impact of time between initiating highly active antiretroviral therapy (HAART) and delivery-duration of antenatal HAART-on perinatal HIV infection.
DESIGN:
We conducted a retrospective cohort analysis of pregnant HIV-infected women in Lusaka, Zambia. Women in our cohort were receiving HAART and had an infant HIV polymerase chain reaction test between 3 and 12 weeks of life.
METHODS:
We examined factors associated with infant HIV infection and performed a locally weighted regression analysis to examine the effect of duration of antenatal HAART on perinatal HIV infection.
RESULTS:
From January 2007 to March 2010, 1813 HIV-infected pregnant women met …


Aha Guidelines For The Management Of Cerebral Venous Thrombosis, Gustavo Saposnik Dec 2010

Aha Guidelines For The Management Of Cerebral Venous Thrombosis, Gustavo Saposnik

Gustavo Saposnik

No abstract provided.