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Full-Text Articles in Medicine and Health Sciences

The Plasma Renin-Angiotensin System In Preeclampsia: Effects Of Magnesium Sulfate., S. Sipes, C. Weiner, Thomas Gellhaus, J. Goodspeed Mar 2013

The Plasma Renin-Angiotensin System In Preeclampsia: Effects Of Magnesium Sulfate., S. Sipes, C. Weiner, Thomas Gellhaus, J. Goodspeed

Thomas M Gellhaus

Two groups of women were studied in a prospective longitudinal fashion to determine the effects of a 2.5-hour infusion of magnesium sulfate upon the renin-angiotensin system. Serum magnesium concentration, angiotensin-converting enzyme concentration, and plasma renin activity were measured at uniform intervals in women with either preeclampsia or preterm labor. Plasma renin activity was significantly lower (3.9 +/- 2.2 versus 6.1 +/- 1.8 ng/mL/minute; P = .004) and angiotensin-converting enzyme significantly higher (47.1 +/- 14 versus 34.0 +/- 10 U/mL; P = .008) in women with preeclampsia than in those with preterm labor. Magnesium infusion was associated with a sustained decline …


Histologic Chorioamnionitis, Microbial Infection, And Prematurity., F. Zlatnik, Thomas Gellhaus, J. Benda, F. Koontz, L. Burmeister Mar 2013

Histologic Chorioamnionitis, Microbial Infection, And Prematurity., F. Zlatnik, Thomas Gellhaus, J. Benda, F. Koontz, L. Burmeister

Thomas M Gellhaus

The purpose of this study was to relate histologic chorioamnionitis to the isolation of microorganisms from the freshly separated chorioamnion in women who had early preterm delivery (before 35 weeks' gestation) following spontaneous labor. Histologic chorioamnionitis was identified in 51 of 95 study subjects. It was more common in the second trimester (72%) than from 27-34 weeks' gestation (33%) (P less than .001). Culture specimens were obtained for aerobic and anaerobic bacteria, yeasts, mycoplasmas, and Chlamydia. Microorganisms were recovered from 38 subjects; all culture reports were negative in 36. A statistically significant association was demonstrated between histologic chorioamnionitis and positive …


Effects Of Magnesium-Sulfate Infusion Upon Plasma Prostaglandins In Preenclampsia And Preterm Labor, S. Sipes, C. Weiner, Thomas Gellhaus, J. Goodspeed Mar 2013

Effects Of Magnesium-Sulfate Infusion Upon Plasma Prostaglandins In Preenclampsia And Preterm Labor, S. Sipes, C. Weiner, Thomas Gellhaus, J. Goodspeed

Thomas M Gellhaus

No abstract provided.


Towards Increasing Health Care In The Developing World: Development Of A Sustainable Site In Bolivia, Thomas M. Gellhaus Mar 2013

Towards Increasing Health Care In The Developing World: Development Of A Sustainable Site In Bolivia, Thomas M. Gellhaus

Thomas M Gellhaus

Most Americans are aware of the great need for health care services in the developing world. In this article, Dr. Thomas Gellhaus provides a compelling story of his volunteer efforts to provide obstetric/gynecologic surgical services to developing countries. Since 1996, he has completed 16 projects in the Dominican Republican, Ecuador, Peru, Bolivia, and Tanzania. In direct response to Dr. Gellhaus’ successes, the Department of Obstetrics and Gynecology at the University of Iowa has made a commitment to develop a sustainable site in Bolivia. Current plans include annual projects that allow physicians and residents to provide valuable medical care to patients …