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Full-Text Articles in Medicine and Health Sciences

Perinatal Outcomes Of Prenatal Probiotic And Prebiotic Administration: An Integrative Review, Leona Vandevusse, Lisa Hanson, Nasia Safdar Oct 2013

Perinatal Outcomes Of Prenatal Probiotic And Prebiotic Administration: An Integrative Review, Leona Vandevusse, Lisa Hanson, Nasia Safdar

College of Nursing Faculty Research and Publications

The purpose of this integrative review was to identify, critique, and synthesize the maternal and neonatal evidence on the prenatal use of probiotics and prebiotics to inform perinatal health professionals. A comprehensive literature search resulted in 37 studies of prenatal probiotics and 1 on antepartal prebiotics published from 1990 through 2011 that reported maternal, fetal, and/or neonatal outcomes. The methodologic quality of the studies reviewed was high, although investigators used different probiotic combinations and inconsistently reported perinatal clinical outcomes. The extraction of perinatal outcome variables resulted in identification of 9 maternal and 5 neonatal categories. Prenatal probiotics significantly reduced the …


Immune Dysregulation And Glucocorticoid Resistance In Minority And Low Income Pregnant Women, Elizabeth J. Corwin, Ying Guo, Kathleen Pajer, Nancy Lowe, Donna O. Mccarthy, Sarah Schmiege, Mary Weber, Thaddeus Pace, Brian Stafford Sep 2013

Immune Dysregulation And Glucocorticoid Resistance In Minority And Low Income Pregnant Women, Elizabeth J. Corwin, Ying Guo, Kathleen Pajer, Nancy Lowe, Donna O. Mccarthy, Sarah Schmiege, Mary Weber, Thaddeus Pace, Brian Stafford

College of Nursing Faculty Research and Publications

Chronic prenatal stress contributes to poor birth outcomes for women and infants. Importantly, poor birth outcomes are most common among minority and low income women. To investigate underlying mechanisms, we tested the hypothesis that chronic stress related to minority or low income status is associated with glucocorticoid resistance as indicated by disruption in the cytokine-glucocorticoid feedback circuit. Home visits were conducted during which 3rd trimester pregnant women completed stress and depression surveys and provided blood for pro- and anti-inflammatory cytokines. Saliva was collected 5 times the preceding day for diurnal cortisol levels. For statistical analyses, women were grouped 3 ways, …


Promoting Abstinence From Alcohol During Pregnancy: Implications From Formative Research, Kathryn France, Robert Donovan, Nadine Henley, Carol Bower, Elizabeth Elliott, Janet Payne, Heather D'Antoine, Anne Bartu Jul 2013

Promoting Abstinence From Alcohol During Pregnancy: Implications From Formative Research, Kathryn France, Robert Donovan, Nadine Henley, Carol Bower, Elizabeth Elliott, Janet Payne, Heather D'Antoine, Anne Bartu

Research outputs 2013

This research developed messages to promote abstinence from alcohol during pregnancy and identified elements that enhance message persuasiveness. An exploratory phase was conducted in 2009 that comprised four focus groups with 23 women inWestern Australia and elicited beliefs and attitudes on alcohol use during pregnancy and motivations for behavior change. Four television concepts were subsequently developed and appraised in five focus groups with 31 participants using standard advertising pretesting questions. The implications for campaigns addressing prenatal alcohol exposure and further research are noted and limitations discussed. Funding was received from Healthway and the National Health and Medical Research Council.


Predictors Of Psychosocial Adaptation To Pregnancy Among Urban African-American Primiparas, Joan M. Visger Jan 2013

Predictors Of Psychosocial Adaptation To Pregnancy Among Urban African-American Primiparas, Joan M. Visger

Wayne State University Dissertations

Psychosocial adaptation to pregnancy among urban African-American women has not been well-researched. The purpose of this study was to examine predictors of psychosocial adaptation to pregnancy and to explore relationships among socioeconomic status, experiences and frequency of discrimination, personal control beliefs, social support, planned pregnancy, and model of health care among urban African-American primiparas using life course theory and Lederman's model of psychosocial adaptation to pregnancy as the framework.

One hundred and nine women participated in this descriptive, cross-sectional, correlational study. Participants were recruited from three clinical sites that provided care using medical and/or midwifery models of care. Study variables …


Hard On Your Heart: A Qualitative Description Of Adolescent Prenatal Stress, Candace Clayton Knight Jan 2013

Hard On Your Heart: A Qualitative Description Of Adolescent Prenatal Stress, Candace Clayton Knight

All ETDs from UAB

Introduction: Pregnancy during adolescence is potentially stressful due to the concurrent tasks of navigating the typically tumultuous adolescent stage of development and the life altering experience of pregnancy (Kaye, 2008). There is a growing body of research linking prenatal stress to poor birth and developmental outcomes such as premature birth and low birth weight infants (K. Keenan, Sheffield, & Boeldt, 2007; Mulder et al., 2002), which makes describing the relatively unexplored perceptions and experience of stress during adolescent pregnancy important. The life course framework, with its emphasis on social, environmental, and family risk factors, has implications for reducing disparities among …