Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 2 of 2
Full-Text Articles in Medicine and Health Sciences
Outcomes From Assisted Reproductive Technology, Bradley Van Voorhis
Outcomes From Assisted Reproductive Technology, Bradley Van Voorhis
Bradley J Van Voorhis
The use of assisted reproductive technology (ART) for treating the infertile couple is increasing in the United States. The purpose of this paper is to review the short-term outcomes after ART. Pregnancy rates after ART have shown nearly continuous improvement in the years since its inception. A number of factors affect the pregnancy rate, with the most important being a woman's age. Certain clinical diagnoses are associated with a poorer outcome from ART, including the presence of hydrosalpinges, uterine leiomyomata that distort the endometrial cavity, and decreased ovarian reserve. Multiple gestations are the major complication after ART. New laboratory techniques, …
Immunohistochemical Localization Of Prostaglandin H Synthase In The Female Reproductive Tract And Endometriosis, Bradley Van Voorhis, P. Huettner, M. Clark, J. Hill
Immunohistochemical Localization Of Prostaglandin H Synthase In The Female Reproductive Tract And Endometriosis, Bradley Van Voorhis, P. Huettner, M. Clark, J. Hill
Bradley J Van Voorhis
Prostaglandin H synthase, also known as cyclooxygenase, is an essential enzyme in prostaglandin synthesis. Using a monoclonal antibody and immunohistochemical techniques, we studied the localization of this enzyme in the female reproductive tract and in endometriosis. In the uterus, prostaglandin H synthase was primarily localized to endometrial epithelium with surface epithelium containing more immunoreactive prostaglandin H synthase than glandular epithelium. Fallopian tube secretory epithelial cells also contained prostaglandin H synthase while ciliated epithelial cells did not. Cervical epithelium and myometrial cells did not contain prostaglandin H synthase. A higher percentage of glands in endometriosis and adenomyosis, as compared with eutopic …