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Alpha Amylase As An Emerging Biomarker Of Microaspiration In Mechanically Ventilated Patients: An Integrative Review Of The Literature, Chloe Chase
Honors Undergraduate Theses
Aims: The purpose of this thesis was to synthesize the current literature on alpha amylase as an emerging biomarker of microaspiration in mechanically ventilated patient.
Methods: The methodology included a review and synthesis of pertinent research articles from 1981-2018, written in English language. Criteria for inclusion in the review were all articles that evaluated α- amylase in tracheal secretions or bronchoalveolar lavage fluid (BAL) as a diagnostic tool for identifying microaspiration. The search yielded 11 studies that were reviewed.
Findings: The findings suggest that once aspiration occurs, the duration of α-amylase in the lungs requires further exploration to assist in …