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Full-Text Articles in Medicine and Health Sciences

Barriers And Facilitators To Anti-Retroviral Therapy Adherence Among Adolescents Aged 10 To 19 Years Living With Hiv In Sub-Saharan Africa: A Mixed-Methods Systematic Review And Meta-Analysis, Londiwe D. Hlophe, Jacques L. Tamuzi, Constance Shumba, Peter S. Nyasulu May 2023

Barriers And Facilitators To Anti-Retroviral Therapy Adherence Among Adolescents Aged 10 To 19 Years Living With Hiv In Sub-Saharan Africa: A Mixed-Methods Systematic Review And Meta-Analysis, Londiwe D. Hlophe, Jacques L. Tamuzi, Constance Shumba, Peter S. Nyasulu

School of Nursing & Midwifery, East Africa

Background: Human Immunodeficiency Virus (HIV) significantly affects adolescents globally, with the sub-Saharan Africa (SSA) reporting a high burden of the disease. HIV testing, treatment, and retention to care are low among adolescents. We conducted a mixed-method systematic review to assess anti-retroviral therapy (ART) adherence; barriers and facilitators to ART adherence and ART outcomes among adolescents living with HIV and on ART in sub-Saharan Africa.

Methods: We conducted searches in four scientific databases for studies conducted between 2010 and March 2022 to identify relevant primary studies. Studies were screened against inclusion criteria and assessed for quality, and data was …


Barriers To Anti-Retroviral Therapy Adherence Among Adolescents Aged 10 To 19 Years Living With Hiv In Sub-Saharan Africa: A Mixed-Methods Systematic Review Protocol, Londiwe D. Hlophe, Jacques L. Tamuzi, Constance Shumba, Peter S. Nyasulu Sep 2022

Barriers To Anti-Retroviral Therapy Adherence Among Adolescents Aged 10 To 19 Years Living With Hiv In Sub-Saharan Africa: A Mixed-Methods Systematic Review Protocol, Londiwe D. Hlophe, Jacques L. Tamuzi, Constance Shumba, Peter S. Nyasulu

School of Nursing & Midwifery, East Africa

Background: Antiretroviral therapy (ART) adherence is fundamental in achieving viral load suppression and consequently attaining positive health outcomes among people living with HIV. However, ART adherence is sub-optimum among adolescents living with HIV (ALHIV) thus the high AIDS-related mortality even after World Health Organization (WHO) revised HIV treatment eligibility guidelines in 2010, 2013 and 2016. Consolidated trends of barriers to ART adherence among ALHIV aged 10 to 19 years in sub-Saharan countries post each eligibility guidelines revision to date are unknown.

Methods and analysis: We will conduct comprehensive search of peer-reviewed and grey literature databases publishing observational studies reporting data …


Barriers And Facilitators Of Linkage To Hiv Care Among Hiv-Infected Young Chinese Men Who Have Sex With Men: A Qualitative Study, Haochu Li, Chongyi Wei, Joseph Tucker, Dianmin Kang, Meizhen Liao, Eleanor Holroyd, Jietao Zheng, Qian Qi, Wei Ma Jan 2017

Barriers And Facilitators Of Linkage To Hiv Care Among Hiv-Infected Young Chinese Men Who Have Sex With Men: A Qualitative Study, Haochu Li, Chongyi Wei, Joseph Tucker, Dianmin Kang, Meizhen Liao, Eleanor Holroyd, Jietao Zheng, Qian Qi, Wei Ma

School of Nursing & Midwifery, East Africa

Background: The Four Free and One Care Policy (HIV/AIDS-related free services) has been in place in China since 2004. However, linkage to human immunodeficiency virus (HIV) care is not yet achieved very well among people living with HIV. We conducted a qualitative study to explore individual and contextual factors that may influence a linkage to HIV care from the perspective of young HIV-infected men who have sex with men (MSM) in a highly centralized HIV care context of China.

Methods: Purposive sampling was used to recruit 21 HIV-infected MSM in Shandong Province, with in-depth interviews conducted between March and July …


Promoting Resilience For Hiv Prevention In Female Sex Workers In Hong Kong: A Randomised Controlled Trial, Winnie W-Y Yuen, William C-W Wong, Catherine S-K Tang, Eleanor Holroyd, Agnes F-Y Tiwari, Daniel Y-T Fong, Weng Y. Chin Oct 2015

Promoting Resilience For Hiv Prevention In Female Sex Workers In Hong Kong: A Randomised Controlled Trial, Winnie W-Y Yuen, William C-W Wong, Catherine S-K Tang, Eleanor Holroyd, Agnes F-Y Tiwari, Daniel Y-T Fong, Weng Y. Chin

School of Nursing & Midwifery, East Africa

Background: Female sex workers are considered a reservoir of HIV and their psychological health has a role to play in HIV infections. In China, commercial sex workers were reported to account for nearly 50% of heterosexual transmission of HIV. Therefore, HIV prevention targeted at mental health could be an innovative strategy in controlling the infection. We aimed to provide an evidence-based resilience-promoting intervention targeting mental health and ultimately safe sexual practices of female sex workers.

Methods: This randomised controlled trial was done at three Hong Kong non-governmental organisations, namely Action for REACH OUT, JJJ Association, and the Society of …


Exploring Unprotected Anal Intercourse Among Newly Diagnosed Hiv Positive Men Who Have Sex With Men In China: An Ethnographic Study, Haochu Li, Eleanor Holroyd, Joseph Lau Jan 2015

Exploring Unprotected Anal Intercourse Among Newly Diagnosed Hiv Positive Men Who Have Sex With Men In China: An Ethnographic Study, Haochu Li, Eleanor Holroyd, Joseph Lau

School of Nursing & Midwifery, East Africa

Background: Unprotected anal intercourse (UAI) is a major pathway towards secondary HIV transmission among men who have sex with men (MSM). We explored the socio-cultural environment and individual beliefs and experiences conducive to UAI in the context of Southern China.

Methods: We employed an ethnographic approach utilizing a socio-ecological framework to conduct repeated in-depth interviews with thirty one newly diagnosed HIV positive MSM as well as participant observations in Shenzhen based healthcare settings, MSM venues and NGO offices.

Results: Some men (6/31) reported continuing to practice UAI after an initial diagnosis of being HIV positive. For MSM who had existing …


The Importance Of Hiv Specialist Services For African Women Living With Hiv In Nottingham: Results Of A Qualitative Study, Eunice Ndirangu, Catrin Evans Jan 2009

The Importance Of Hiv Specialist Services For African Women Living With Hiv In Nottingham: Results Of A Qualitative Study, Eunice Ndirangu, Catrin Evans

School of Nursing & Midwifery, East Africa

This article reports the results of a qualitative study of the experiences of African women living with HIV in Nottingham, UK. Globally, sub-Saharan Africa is the region most severely affected by the HIV pandemic [1]. This pattern is also reflected in the UK where African migrants make up 27% of those diagnosed with HIV despite the fact that they constitute less than 1% of the population [2-4]. Healthcare staff play a central role in meeting the prevention and care needs of people living with HIV/AIDS [5]. In contexts of increasing migration, health workers are called upon to recognise the diverse …


'People Are Creating Policy Up There, They Are Not Coming Down': Nurses' Views On The Expansion Of Routine Provider-Initiated Hiv Testing And Counselling In Nairobi, Kenya., Catrin Evans, Eunice Ndirangu Jan 2009

'People Are Creating Policy Up There, They Are Not Coming Down': Nurses' Views On The Expansion Of Routine Provider-Initiated Hiv Testing And Counselling In Nairobi, Kenya., Catrin Evans, Eunice Ndirangu

School of Nursing & Midwifery, East Africa

In this report, we present selected findings from an exploratory piece of qualitative research on HIV testing that was undertaken in 2007-2008 with nurses in Nairobi, Kenya. At the same time, we share our own story of how this research came about and how NHIVNA research funding was able to lay the foundations for a larger study that will hopefully give voice to patients and HIV nurses in Nairobi and will develop HIV nursing research capacity in the country.