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Full-Text Articles in Medicine and Health Sciences

The Development Of An Innovative Mentorship Experience For An Online Rn-To-Bsn Program, Melissa Wholeben, Gloria Mckee, Audrey Tolouian, Diane Rankin Nov 2020

The Development Of An Innovative Mentorship Experience For An Online Rn-To-Bsn Program, Melissa Wholeben, Gloria Mckee, Audrey Tolouian, Diane Rankin

Nursing Faculty Publications

The Institute of Medicine, Carnegie Foundation and the American Association of Colleges of Nursing (AACN) initially accelerated the movement to increase the number of Baccalaureate (BSN) prepared nurses in the workforce. Research demonstrated lower mortality rates, fewer medication errors and positive outcomes linked to nurses prepared at the BSN and higher levels. The purpose of this article is to describe the steps utilized in the development of an innovative mentorship project that provides mentored clinical practice experiences to students enrolled in an RN-to-BSN program delivered 100% online. This mentorship project was developed with two main aims in mind: 1) To …


Herbal Medicines In The Treatment Of Coronavirus Disease 2019 (Covid-19), Audrey C. Tolouian, Maryam Khosravian, Hedieh Ragati Haghi, Alireza Bolourian, Zahra Mojtahedi, Masoumeh Asgharpour, Amirhesam Alirezaei Nov 2020

Herbal Medicines In The Treatment Of Coronavirus Disease 2019 (Covid-19), Audrey C. Tolouian, Maryam Khosravian, Hedieh Ragati Haghi, Alireza Bolourian, Zahra Mojtahedi, Masoumeh Asgharpour, Amirhesam Alirezaei

Nursing Faculty Publications

Coronavirus disease 2019 (COVID-19), caused by a novel coronavirus, started in livestock within the markets of Wuhan, China and was consequently spread around the world. The virus has been rapidly spread worldwide due to the outbreak. COVID-19 is the third serious coronavirus outbreak in less than 20 years after Severe Acute Respiratory Syndrome (SARS) in 2003 and Middle East Respiratory Syndrome (MERS) in 2012. The novel virus has a nucleotide identity closer to that of the SARS coronavirus than that of the MERS coronavirus. Since there is still no vaccine, the main ways to improve personal immunity against this disease …


The Pandemic Need For Mindfulness, Audrey C. Tolouian, Melissa Wholeben Aug 2020

The Pandemic Need For Mindfulness, Audrey C. Tolouian, Melissa Wholeben

Nursing Faculty Publications

In a trauma facility, it is important that there be training for the healthcare providers that gives them tools to manage their internal reactions to the day-to-day events, as well as create a safe space and encourage a sense of community. For healthcare workers in high-trauma areas- such as the new COVID-19 units, post-traumatic stress syndrome (PTSD) has been on the rise, in 2011, 14% of nurses were diagnosed, in 2019 an estimated 40% of nurses suffer from the disorder. With the small amount of 18% of nurses feeling they are prepared with proficient self-care skills to manage the effects …


Lung Cancer And Kidney Injury: An Updated Review, Bhargav Patel, Mohammad Ebrahimi Kalan, Maryam Khosravian, Audrey C. Tolouian, Ramin Tolouian, Mahnaz Aboufazeli, Masoumeh Asgharpour, Amirhesam Alirezaei Aug 2020

Lung Cancer And Kidney Injury: An Updated Review, Bhargav Patel, Mohammad Ebrahimi Kalan, Maryam Khosravian, Audrey C. Tolouian, Ramin Tolouian, Mahnaz Aboufazeli, Masoumeh Asgharpour, Amirhesam Alirezaei

Nursing Faculty Publications

Lung cancer is the leading cause of cancer deaths worldwide, accounting for an estimated 1.8 million deaths. Lung cancer is also the most common primary cancer leading to soft tissue (ST) metastasis. Renal disease may occur as a direct or indirect consequence of the cancer itself (e.g., postrenal obstruction, compression, or infiltration), its treatment (e.g., radiotherapy or chemotherapy), or its related complications (e.g., opportunistic infection). Existing evidence shows that the most frequent primary solid tumor responsible for renal metastasis is pulmonary carcinoma, followed by gastric, breast, soft tissue, and thyroid carcinomas. Chronic kidney disease is a potential risk factor in …


When Mistakes Happen: Using Aone Principles Of A Healthful Practice Environment, Karen Fowler Aug 2020

When Mistakes Happen: Using Aone Principles Of A Healthful Practice Environment, Karen Fowler

Nursing Faculty Publications

Whether medical errors will occur is not the question. When and to what degree of harm will the patient, nursing staff, and organization experience is a more valid question. The nurse leader’s ability to navigate staff through the aftermath of a negative patient event has far-reaching consequences. Errors impact the organization financially and reputationally, and can have devastating results for the nursing staff. This paper explores the use of AONL’s 9 elements of a healthful practice environment. These elements offer structure and guidance for the nurse leader to mindfully lead the nursing staff through a difficult situation while enhancing staff …


Taking Time To Enjoy Some Coffee! Adding Mindfulness To The Curriculum, Audrey C. Tolouian Jul 2020

Taking Time To Enjoy Some Coffee! Adding Mindfulness To The Curriculum, Audrey C. Tolouian

Nursing Faculty Publications

No abstract provided.


Covid-19: Outcomes For Trauma-Impacted Nurses And Nursing Students, Karen Fowler, Melissa Wholeben Jun 2020

Covid-19: Outcomes For Trauma-Impacted Nurses And Nursing Students, Karen Fowler, Melissa Wholeben

Nursing Faculty Publications

No abstract provided.


Herbal Antioxidants And Renal Ischemic-Reperfusion Injury; An Updated Review, Masoumeh Asgharpour, Audrey C. Tolouian, Lakkakula Vks Bhaskar, Ramin Tolouian, Nilofar Massoudi May 2020

Herbal Antioxidants And Renal Ischemic-Reperfusion Injury; An Updated Review, Masoumeh Asgharpour, Audrey C. Tolouian, Lakkakula Vks Bhaskar, Ramin Tolouian, Nilofar Massoudi

Nursing Faculty Publications

Renal ischemia-reperfusion (RIR) is a pathological condition due to transient restriction of blood flow to the kidneys, which is followed by the subsequent recovery of perfusion and re-oxygenation. RIR injury contributes to the progression of renal dysfunction including acute kidney injury (AKI) in native and renal allograft transplant. The generation of reactive oxygen species (ROS) during oxidative stress contributes to the occurrence of RIR. Hence, the use of antioxidant compounds can improve oxidative stress due to RIR. This review highlights herbal antioxidant efficacy against RIR injury. The findings of this study indicate that antioxidant compounds with herbal origin could reduce …


Renal Transplantation In A Patient With Mhy9-Related Disease; A Case Report, Sepideh Zununi Vahed, Bahram Niknafs, Hamid Noshad, Ramin Tolouian, Mohammadali Mohajel Shoja, Audrey C. Tolouian, Mohammadreza Ardalan May 2020

Renal Transplantation In A Patient With Mhy9-Related Disease; A Case Report, Sepideh Zununi Vahed, Bahram Niknafs, Hamid Noshad, Ramin Tolouian, Mohammadali Mohajel Shoja, Audrey C. Tolouian, Mohammadreza Ardalan

Nursing Faculty Publications

MYH9-related diseases (MYH9-RD) are clinically represented by thrombocytopenia, large platelets, proteinuria and various degrees of renal dysfunction. We present a 25-year-old male with thrombocytopenia, large platelets, renal dysfunction and proteinuria. Gene sequencing of whole exons of MYH9 gene confirmed the diagnosis of MYH9-related disorder and revealed single nucleotide polymorphisms (SNPs) in the introns 13 (rs3752462) and 14 (rs2413396) and a mutation in exon 26 of MYH9 gene. Our result supported the possibility of non-coding SNPs involvement in the pathogenicity of the MYH9-RD disease and successful renal transplant in this patient.


The Impact Of Metformin In Chronic Kidney Disease-Mineral And Bone Disorder, Rohollah Masumi, Ramin Tolouian, Audrey C. Tolouian, Leila Mohmoodnia May 2020

The Impact Of Metformin In Chronic Kidney Disease-Mineral And Bone Disorder, Rohollah Masumi, Ramin Tolouian, Audrey C. Tolouian, Leila Mohmoodnia

Nursing Faculty Publications

Chronic kidney disease-mineral and bone disorder (CKD-MBD) is a disorder of mineral and bone metabolism due to chronic kidney disease (CKD). Bone disease and mortality are more common in patients with CKD. In addition of antidiabetic properties of metformin (MET), it possesses anti-inflammatory, anti-fibrotic properties and increases the markers of osteogenic effects. Therefore, it improves bone quality and decreases the risk of fractures in patients with type 2 diabetes. Metformin can also inhibit arterial calcification, maintain calcium-phosphorus balance, decrease cellular infiltration, fibrosis, and inflammation in kidney. Based on evidence, the prevalence of lactic acidosis due to metformin in patients with …


The Footprint Of Androgen Sensitive Serine Protease (Tmprss2) In Gender Mortality With Covid-19, Sepideh Zununi Vahed, Shahram Ghiyasvand, Ramin Tolouian, Hamid Noshad, Audrey C. Tolouian, Mohammadali Mohajel Shoja, Mohammadreza Ardalan May 2020

The Footprint Of Androgen Sensitive Serine Protease (Tmprss2) In Gender Mortality With Covid-19, Sepideh Zununi Vahed, Shahram Ghiyasvand, Ramin Tolouian, Hamid Noshad, Audrey C. Tolouian, Mohammadali Mohajel Shoja, Mohammadreza Ardalan

Nursing Faculty Publications

Male gender is an obvious risk factor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and mortality rate is higher in men than women. Undoubtedly, gender-related behavioral factors, such as higher amounts of smoking, alcohol consumption, and biological differences in immune systems could make males more vulnerable. The role of androgen-responsive elements (AREs) of transmembrane serine proteases type II (TMPRSS2) gene as one of the major players of male dominancy in severe COVID-19 infection has been under appreciated and needs to be clarified.


Healthcare Educational Practices On Stigmatism Of Chronic Illness: A Qualitative Narrative Study, Audrey C. Tolouian Apr 2020

Healthcare Educational Practices On Stigmatism Of Chronic Illness: A Qualitative Narrative Study, Audrey C. Tolouian

Nursing Faculty Publications

The problem is the identified stigma related to certain diseases affecting the quality of care provided by healthcare workers. Somatic diseases or those with vague signs and symptoms are subject to various stigmas. Due to the lack of a known cause of fibromyalgia, the disease is subject to stigma. The purpose of this qualitative narrative study was to bring awareness to healthcare educators about the potential impact of stigma. Educators may transfer stigma to their students, which may affect the quality of care. The research question guiding this study was, “How might healthcare educators’ perceptions of chronic illness transfer to …


Covid-19 Interactions With Angiotensin-Converting Enzyme 2 (Ace2) And The Kinin System; Looking At A Potential Treatment, Ramin Tolouian, Sepideh Zununi Vahed, Shahram Ghiyasvand, Audrey C. Tolouian, Mohammadreza Ardalan Mar 2020

Covid-19 Interactions With Angiotensin-Converting Enzyme 2 (Ace2) And The Kinin System; Looking At A Potential Treatment, Ramin Tolouian, Sepideh Zununi Vahed, Shahram Ghiyasvand, Audrey C. Tolouian, Mohammadreza Ardalan

Nursing Faculty Publications

The novel coronavirus disease 2019 (COVID-19) is a rapidly expanding infection around the world. The world Health Organization (WHO) in March 2020 announced the Coronavirus pandemic. This infection causes many deaths on daily basis. Therapeutic options are currently limited. It is revealed that COVID-19 binds to human angiotensin-converting enzyme 2 (ACE2) to enter the host cells. One of the activities of ACE2 is hydrolyzing the active bradykinin metabolite [des-Arg973] BK (DABK). A decreased activity or reducing expression of ACE2 by the virus impairs the inactivation of DABK. This enhances its signaling through the bradykinin B1 receptor (BKB1R) and could lead …