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Articles 1 - 4 of 4
Full-Text Articles in Medicine and Health Sciences
The Effects Of Astrocytic Derived Insulin-Like Growth Factor (Igf-1) On Cognition And Astrocytes, Destiny Wilson
The Effects Of Astrocytic Derived Insulin-Like Growth Factor (Igf-1) On Cognition And Astrocytes, Destiny Wilson
Honors Theses
Insulin-like growth factor 1 (IGF-1) is a neuroendocrine signaling hormone that plays a vital role in growth and development, as well as learning and memory. Inhibition of this hormone results in cognitive impairments like those seen with age-related decline. While a majority of research has focused on the role of IGF-1 on neurons, the role of astrocytes still needs to be explored. Our research investigates how astrocytes and cognition are affected as a result of direct regulation of localized IGF-1 production in early development and after puberty. Preliminary studies in our laboratory established a connection between IGF-1 and glial fibrillary …
Effects Of Music Exposure On Autobiographical Memory In Alzheimer's Patients: A Systematic Review And Meta-Analysis, Gregory Vance
Effects Of Music Exposure On Autobiographical Memory In Alzheimer's Patients: A Systematic Review And Meta-Analysis, Gregory Vance
Honors Theses
The progression of Alzheimer’s disease is primarily characterized by a loss of memory concerning past events, as well as a lack in ability to create new memories. While this spans across many subsets of memory, such as recognition, recall, and autobiographical memory, there seems to be a lesser impact on musical memory in those with Alzheimer’s. Multiple studies have suggested that exposure to music and introduction of music therapy can even improve other aspects of memory in Alzheimer’s patients. This systematic review and meta-analysis sought to examine the relationship between music exposure and autobiographical memory specifically. A pool of electronic …
Efficacy Of Δ-9-Tetrahydrocannabinol For Hiv-Related Neuropathic Pain, Kaia Horne
Efficacy Of Δ-9-Tetrahydrocannabinol For Hiv-Related Neuropathic Pain, Kaia Horne
Honors Theses
Despite the availability and success of antiretroviral therapeutics, ~30% of patients living with HIV experience neuropathic pain that is often intractable. The mechanisms are not known, but there is evidence to support a role for the HIV virotoxins, Tat and/or gp120, which can damage or degenerate neurons and peripheral nerves. One mechanism by which Tat and gp120 promote nerve damage involves the stimulation of proinflammatory cytokine production from immune cells which can damage or kill bystander cells. Notably, compounds found in Cannabis exert anti-inflammatory effects and many studies report HIV patients to consume more marijuana than seronegative individuals. When people …
Effects Of Acute Exercise Intensity On Memory: Considerations Of Timing And Aerobic Endurance, William Meyers, Caroline Loeb, Mary Collins West, Bailey Bass
Effects Of Acute Exercise Intensity On Memory: Considerations Of Timing And Aerobic Endurance, William Meyers, Caroline Loeb, Mary Collins West, Bailey Bass
Honors Theses
The primary objective of this study was to find the optimal acute exercise intensity and post-exercise recovery time to enhance memory retention. A secondary objective of study was to evaluate the influence of aerobic endurance on memory and whether endurance capacity interacts with exercise intensity and post-exercise recovery period to influence memory performance. Participants were 54 undergraduate and graduate students at the University of Mississippi, with an age range of 18-23 years. Participants completed 13 visits in total. The first visit evaluated their aerobic endurance, with the remaining 12 visits including a 3 (Intensity: Control, Moderate, Vigorous) by 4 (Post-Exercise …