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Neurology

Selected Works

Parkinson disease

Articles 1 - 6 of 6

Full-Text Articles in Medicine and Health Sciences

A New Treatment For Psychosis In Parkinson’S Disease, Kevin J. Black Jul 2016

A New Treatment For Psychosis In Parkinson’S Disease, Kevin J. Black

Kevin J. Black, MD

This is an update on treatment of hallucinations and delusions in Parkinson disease, including the recently approved Nuplazid™ (pimavanserin).


Parkinson’S Disease Psychosis: A Roundtable Discussion, Jennifer G. Goldman, Rajesh Pahwa, Stuart H. Isaacson, Kevin J. Black Dec 2014

Parkinson’S Disease Psychosis: A Roundtable Discussion, Jennifer G. Goldman, Rajesh Pahwa, Stuart H. Isaacson, Kevin J. Black

Kevin J. Black, MD

A discussion about diagnosing and managing Parkinson's disease psychosis, with 3 neurologists and a neuropsychiatrist, all from movement disorders centers. Supplement to Clinical Neurology News. Disclosure: supplement was supported by ACADIA Pharmaceuticals.


Depression In Parkinson Disease, Kevin J. Black Jul 2013

Depression In Parkinson Disease, Kevin J. Black

Kevin J. Black, MD

Many patients with Parkinson disease develop depressive symptoms severe enough to discuss with their physician. Below I will address some of the questions we hear from patients and families about depression in Parkinson disease.


A Fixed-Dose Randomized Controlled Trial Of Olanzapine For Psychosis In Parkinson Disease, Michelle J. Nichols, Johanna M. Hartlein, Meredith Ga Eicken, Brad A. Racette, Kevin J. Black Jul 2013

A Fixed-Dose Randomized Controlled Trial Of Olanzapine For Psychosis In Parkinson Disease, Michelle J. Nichols, Johanna M. Hartlein, Meredith Ga Eicken, Brad A. Racette, Kevin J. Black

Kevin J. Black, MD

Background: Psychosis is a common and debilitating side effect of long-term dopaminergic treatment of Parkinson disease (PD). While clozapine is an effective treatment, the need for blood monitoring has limited its first-line use.

Objective: Since olanzapine shows similar receptor affinity to clozapine, we hypothesized that it might be an effective alternative to clozapine for treatment of drug-induced psychosis (DIP) in PD, and that lower doses than usual might make it tolerable.

Methods: In 1998-2003 we conducted a four-week, double-blind, placebo-controlled, parallel group, fixed-dose trial of olanzapine (0, 2.5mg, or 5mg) in 23 PD patients with DIP while allowing for clinically …


Hallucinations—Psychosis Related To Parkinson’S Disease, Kevin J. Black Oct 2011

Hallucinations—Psychosis Related To Parkinson’S Disease, Kevin J. Black

Kevin J. Black, MD

No abstract provided.


Depression In Pd, Kevin J. Black Aug 1998

Depression In Pd, Kevin J. Black

Kevin J. Black, MD

No abstract provided.