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Full-Text Articles in Medicine and Health Sciences
Renal Involvement In Systemic Lupus Erythematosus In Pakistan, Malik Anas Rabbani, Muhammad Hammad Tahir, Bilal Karim Siddiqui, Bushra Ahmad, A Shamim, Syed Mansoor Shah, Aasim Ahmad
Renal Involvement In Systemic Lupus Erythematosus In Pakistan, Malik Anas Rabbani, Muhammad Hammad Tahir, Bilal Karim Siddiqui, Bushra Ahmad, A Shamim, Syed Mansoor Shah, Aasim Ahmad
Section of Nephrology
Objective: To find the prevalence of lupus nephritis, delineate its clinical, immunological and therapeutic characteristics and compare them with the data worldwide.PATIENTS AND Methods: Between 1985 and 2001, 198 patients with SLE fulfilling the clinical and laboratory criteria of the American Rheumatism Association (ARA) admitted to the hospital were studied by means of a retrospective review of their records.Results: Renal involvement was found in 89 (45%) patients. Biopsy showed lupus nephritis in 42 patients; there were 9 male and 33 females. Mean age at initial presentation was 27 years and mean duration of follow-up was 2 .3 years. The histological …
Serum Creatinine As Marker Of Kidney Function In South Asians: A Study Of Reduced Gfr In Adults In Pakistan, Tazeen H. Jafar, Christopher H. Schmid, Andrew S. Levey
Serum Creatinine As Marker Of Kidney Function In South Asians: A Study Of Reduced Gfr In Adults In Pakistan, Tazeen H. Jafar, Christopher H. Schmid, Andrew S. Levey
Section of Nephrology
Migrant populations of South Asian origin have a higher risk for chronic kidney disease than the native whites. Several formulas have been developed to estimate kidney function from serum creatinine concentration. However, none of these has been validated in the South Asian population, which generally has different muscle mass composition than whites. A population-based cross-sectional study was performed on 262 individuals who were aged > or = 40 yr in Karachi, Pakistan. Reduced GFR was defined as creatinine clearance (Ccr) measured in 24-h urine collection of /min per 1.73 m2. Creatinine excretion was compared with age- and gender-matched white individuals by …