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Neoplasms

University of Tennessee Health Science Center

Acute Lymphoblastic Leukemia

Publication Year

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Full-Text Articles in Medicine and Health Sciences

Sleep, Fatigue And Caregiver Burden In Parents Of Children With Acute Lymphoblastic Leukemia (All), Jerithea Tidwell May 2008

Sleep, Fatigue And Caregiver Burden In Parents Of Children With Acute Lymphoblastic Leukemia (All), Jerithea Tidwell

Theses and Dissertations (ETD)

Parents often report that their child diagnosed with acute lymphoblastic leukemia (ALL) and receiving steroid therapy experience altered sleep patterns, fatigue, irritability, and other behavioral changes. As a consequence, parents may experience altered sleep, fatigue, and increased caregiver burden. If so, the differences seen in parental sleep efficiency and sleep duration may be attributed to the child experiencing altered sleep secondary to receiving dexamethasone. The purpose of this study was to describe, caregiver sleep, fatigue, and caregiver burden immediately before and during their child’s dexamethasone pulse in continuation therapy for ALL and to compare parent quality of sleep and fatigue …


Hand-Wrist Bone Age In Children Treated For Acute Lymphoblastic Leukemia, Mary Elizabeth Martin May 2006

Hand-Wrist Bone Age In Children Treated For Acute Lymphoblastic Leukemia, Mary Elizabeth Martin

Theses and Dissertations (ETD)

Acute Lymphoblastic Leukemia (ALL) is the most common malignancy of childhood, constituting 31 percent of all childhood malignancies. Treatment strategies to target ALL include chemotherapeutic agents, irradiation of the neck and/or spine, and bone marrow transplantation. The aggressive nature of antineoplastic therapies often produces numerous craniofacial and dental sequelae as well as additional harmful effects to the entire body. Cranial irradiation may adversely affect the hypothalamic-pituitary axis decreasing growth hormone production. Consequently, children with ALL may experience a transient or permanent reduction in growth iatrogenically. Hand-wrist radiographs are valuable for evaluating maturational status in children with ALL. These radiographs allow …