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Full-Text Articles in Medicine and Health Sciences

Tomographic And Histological Analyses Of Ectopic Calcification Associated With Diffuse Idiopathic Skeletal Hyperostosis (Dish), Dale Edward Fournier Aug 2018

Tomographic And Histological Analyses Of Ectopic Calcification Associated With Diffuse Idiopathic Skeletal Hyperostosis (Dish), Dale Edward Fournier

Electronic Thesis and Dissertation Repository

Diffuse idiopathic skeletal hyperostosis (DISH) is a non-inflammatory spondyloarthropathy characterised by the formation of ectopic calcifications of the ligaments/enthuses along the anterolateral aspect of the vertebral column. Despite affecting 15-25% of North Americans over the age of 50, the aetiology of DISH is poorly understood and there are no disease modifying treatments. Our discovery-based approach implemented a transdisciplinary research team to study the basic biology, imaging science, clinical anatomy and significance of DISH in humans. Our novel characterisation defined distinct morphological presentations of ectopic calcifications associated with DISH in cadaveric specimens using micro-computed tomography imaging. Subsequent histopathological analyses demonstrated that …


Parkinson's Disease: Promoting Wellbeing Through Creation Health, Rupelin Pichot Jan 2018

Parkinson's Disease: Promoting Wellbeing Through Creation Health, Rupelin Pichot

DNP Research Projects

There are approximately 1.5 million Americans affected by Parkinson’s disease (PD). In spite of medications and technological advances in managing the disease, patients with PD still live poor quality lives. Therefore, effective natural interventions are essential in promoting wellbeing and quality of life among PD patients. This research study aimed to examine the usefulness and efficacy of a PD brochure designed especially for PD patients and their caregivers by utilizing CREATION Health (CH) principles to promote wellbeing and quality of life in patients with PD. This study employed mixed methods of quantitative and qualitative research designs to evaluate the design, …


Muscle Synergy During A Single Leg Standing Test In Ambulatory Children With Cerebral Palsy, Brennan L. Smith Jan 2018

Muscle Synergy During A Single Leg Standing Test In Ambulatory Children With Cerebral Palsy, Brennan L. Smith

Theses and Dissertations--Kinesiology and Health Promotion

INTRODUCTION: Cerebral Palsy (CP) is a sensorimotor disorder characterized by dysfunctional motor coordination, balance problems, and loss of selective motor control. Motor coordination exhibited as co-contraction, has been subjectively quantified using gait analysis, but recent studies have begun to objectively analyze the amount of co-contraction by collecting electromyography (EMG) data. Center of pressure excursion (COPE) measurements collected during a single leg standing test (SLST) have shown to be more valid measurements of balance in populations with motor disabilities than a SLST alone. A recent study has correlated increased COPE velocity with a lower fall risk as determined by reported fall …