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Do Antipsychotic Dose Reduction Trials Result In Worsening Behavior Among Nursing Home Residents With Dementia: A Systematic Review Of The Literature, Jennifer Tjia, Abir O. Kanaan, Jennifer L. Donovan
Do Antipsychotic Dose Reduction Trials Result In Worsening Behavior Among Nursing Home Residents With Dementia: A Systematic Review Of The Literature, Jennifer Tjia, Abir O. Kanaan, Jennifer L. Donovan
Jennifer Tjia
Background: While federal regulations require gradual dose reduction trials of antipsychotics prescribed for behavior management in nursing home (NH) residents with dementia, widespread concern about precipitating behavioral disturbances limits implementation. We conducted a systematic review of clinical trials reducing antipsychotic drug use in NH residents to determine best dose reduction practices and risk of behavior escalation.
Methods: A comprehensive literature search was conducted in MEDLINE, EMBASE, and International Pharmaceutical Abstracts between January 1970 and October 2011 using the terms “antipsychotic agent or neuroleptic agent,” “dementia,” “nursing homes,” and “withdrawal.” One investigator reviewed abstracts for inclusion based on: English-language, …
Knowledge Of And Perceived Need For Evidence-Based Educational Materials About Antipsychotic Medication Safety By Nursing Home Staff, Celeste A. Lemay, Sarah Foy, Kathleen M. Mazor, Leslie R. Harrold, Jennifer L. Donovan, Abir O. Kanaan, Becky A. Briesacher, Jerry H. Gurwitz, Jennifer Tjia
Knowledge Of And Perceived Need For Evidence-Based Educational Materials About Antipsychotic Medication Safety By Nursing Home Staff, Celeste A. Lemay, Sarah Foy, Kathleen M. Mazor, Leslie R. Harrold, Jennifer L. Donovan, Abir O. Kanaan, Becky A. Briesacher, Jerry H. Gurwitz, Jennifer Tjia
Jennifer Tjia
Background: Given the widespread overuse of antipsychotic medications among US nursing home (NH) residents, we sought to identify knowledge of and perceived need for the AHRQ Comparative Effectiveness Research Summary Guide (CERSG) “Off-Label Use of Atypical Antipsychotic Drugs”.
Methods: We conducted a baseline needs assessment with 12 NHs participating in a randomized controlled trail evaluating evidence dissemination strategies. Using a mixed method approach, we conducted in-depth assessments of knowledge, attitudes, and practice behavior using telephone interviews with NH leadership (administrators, directors of nursing [DON], and medical directors), and questionnaires with NH leadership, consultant pharmacists and direct care staff. …