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Histological And Ultrastructural Study Of Silver Nanoparticles Toxicity And The Possible Protective Effect Of Vitamin C On Submandibular Salivary Glands Of Albino Rats, Mohamed Shamel, Dalia Riad, Mahmoud Al Ankily

Dentistry

Introduction: Despite silver nanoparticles (AgNPs) beneficial effect in many fields, it has been shown that AgNPs can induce toxic effects. Cytotoxic effect of AgNPs is related to the increased release of reactive oxygen species (ROS) which may lead to cell death. Natural antioxidant scavengers like vitamin C have the capacity to bind and neutralize ROS thus having a vital role in cellular defense against oxidative stress. Objective: The objective of the current study was to assess the cytotoxic impact of AgNPs on the submandibular salivary glands of Albino rats and to reveal the potential antioxidant influence of vitamin C to …