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Medicine and Health Sciences Commons

Open Access. Powered by Scholars. Published by Universities.®

Medical Toxicology

Wright State University

2002

Articles 1 - 2 of 2

Full-Text Articles in Medicine and Health Sciences

Phosphoglycan Messengers And Their Medical Uses (Sle), Khalid M. Elased, Khalid A. Gumaa, Hassan Rahmoune, Thomas Rademacher, J. B. De Souza Jan 2002

Phosphoglycan Messengers And Their Medical Uses (Sle), Khalid M. Elased, Khalid A. Gumaa, Hassan Rahmoune, Thomas Rademacher, J. B. De Souza

Pharmacology and Toxicology Faculty Publications

PPhosphoglycan messengers (PGMs) which are carbohydrate derivatised phosphatidyl cyclitols are disclosed, together with the finding that these substances are biologically active, especially in modulating plasma cholesterol, plasma triglycerides and/or high density lipoprotein levels and/or modulating the LDL:HDL ratio, and for the treatment of lipodystrophy or dyslipidemia. These compounds are distinct from GPI-anchors disclosed in the prior art as these GPI-anchors are protein linked and are not biologically active.


Phosphoglycan Messengers And Their Medical Uses (Lipidemia), Khalid M. Elased, Khalid A. Gumaa, Hassan Rahmoune, Thomas Rademacher Jan 2002

Phosphoglycan Messengers And Their Medical Uses (Lipidemia), Khalid M. Elased, Khalid A. Gumaa, Hassan Rahmoune, Thomas Rademacher

Pharmacology and Toxicology Faculty Publications

Phosphoglycan messengers (PGMs) which are carbohydrate derivatised phosphatidyl cyclitols are disclosed, together with the finding that these substances are biologically active, e.g. in lowering blood glucose levels. These compounds are distinct from GPI-anchors disclosed in the prior art as these GPI-anchors are protein linked and are not biologically active.