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Systematic review

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Multimodal Secondary Prevention Behavioral Interventions For Tia And Stroke: A Systematic Review And Meta-Analysis., Maggie Lawrence Mar 2015

Multimodal Secondary Prevention Behavioral Interventions For Tia And Stroke: A Systematic Review And Meta-Analysis., Maggie Lawrence

Dr. Maggie Lawrence

Background Guidelines recommend implementation of multimodal interventions to help prevent recurrent TIA/stroke. We undertook a systematic review to assess the effectiveness of behavioral secondary prevention interventions.

Strategy Searches were conducted in 14 databases, including MEDLINE (1980-January 2014). We included randomized controlled trials (RCTs) testing multimodal interventions against usual care/modified usual care. All review processes were conducted in accordance with Cochrane guidelines.

Results Twenty-three papers reporting 20 RCTs (6,373 participants) of a range of multimodal behavioral interventions were included. Methodological quality was generally low. Meta-analyses were possible for physiological, lifestyle, psychosocial and mortality/recurrence outcomes. Note: all reported confidence intervals are 95%. …


Review Of Natural Orifice Translumenal Endoscopic Surgery (Notes) For Intra-Abdominal Surgery: Experimental Models, Techniques And Applicability To The Clinical Setting, E Della Flora, T G. Wilson, I J. Martin, N A. O'Rourke, Guy Maddern Jan 2008

Review Of Natural Orifice Translumenal Endoscopic Surgery (Notes) For Intra-Abdominal Surgery: Experimental Models, Techniques And Applicability To The Clinical Setting, E Della Flora, T G. Wilson, I J. Martin, N A. O'Rourke, Guy Maddern

Guy Maddern

Objective: Evaluation of models, techniques, outcomes, pitfalls and applicability to the clinical setting of natural orifice translumenal endoscopic surgery (NOTES) for performing intra-abdominal surgery through a systematic review of the literature. Summary Background Data: NOTES has attracted much recent attention for its potentail to allow traditional surgical procedures to be performed entirely through a natural orifice. Amid the excitement for potentially scar-free surgery and abolishment of dermal incision-related complications, the safety and efficacy of this new surgical technology must be evaluated. Methods: studies were identified by searching MEDLINE, EMBASE, CINAHL, Current Contents, Cochrane Library, Entrez PubMed, Clinical Trials Database, National …