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Anti-Dfs70 As Nonsystemic Autoimmune (Primary Billiar Cholangitis) Concomitant Disease Marker In Systemic Lupus Erythematosus, Yasjudan Rastrama Putra, Deshinta Putri Mulya, Fahmi Indrarti

Jurnal Penyakit Dalam Indonesia

Anti-dense fine speckled 70 (DFS70) is known as a non-systemic autoimmune marker. It is only found in 1% of systemic autoimmune patients and 2–22% in healthy population. To the best of our knowledge, no anti-DFS70 positive has been reported in systemic lupus erythematosus (SLE) patients with primary billiary cholangitis (PBC) comorbidities. We reported a 40-year-old woman that was diagnosed with SLE 1-month before, came to the hospital due to seven days of fatigue, loss of appetite, icteric, arthralgia, hair loss, and unexplained fever. Total bilirubin was 9.46 mg/dl, direct bilirubin 7.73 mg/dl, gamma-glutamyl transferase (GGT) 503 U/L, alkaline phosphatase (ALP) …