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Possible Protective Effect Of Anisum Oil On Aspartame Induced Changes In Cerebellum Of Albino Rats (Light And Electron Microscopic Study), Mohammed Sobhey, Mahmoud Elnaggar, Mohammed Autifi
Possible Protective Effect Of Anisum Oil On Aspartame Induced Changes In Cerebellum Of Albino Rats (Light And Electron Microscopic Study), Mohammed Sobhey, Mahmoud Elnaggar, Mohammed Autifi
Al-Azhar International Medical Journal
Background: Aspartame (ASP) is an artificial sweetener which might caused changes in cerebellum. Objective: To evaluate the histological changes in cerebellar cortex of albino rats treated by aspartame and the impact of co-treatment with anisum oil. Methods: The study done at Pharmacology Department lab., Faculty of Medicine, Al-Azhar University, between January and March 2020. Sixty rats divided into four equal groups: Group 1 (control group): served as control animals. Group 2 (anisum oil): received 0.5 ml/kg/d/b wt. of anisum oil once daily. Group 3 (ASP group): received daily 250 mg/kg. body wt. of ASP dissolved in distilled water and given …