Medicine and Health Sciences Commons^™

Is Amitriptyline Effective In Reducing Headache Days In Pediatric Patients With Migraines And Chronic Headaches Compared To Topiramate, Propranolol, Or No Treatment?, Megan N. Hall

PCOM Physician Assistant Studies Student Scholarship

Objective: The objective of this selective EBM review is to determine whether or not “Is amitriptyline effective in reducing headache days in pediatric patients with migraines and chronic headaches compared to topiramate, propranolol, or no treatment?”

Study design: Systematic review of two randomized control trials (RCTs) and one case series published in peer-reviewed journals in English after 2007.

Data Sources: Two RCTs and one case series were found using PubMed.

Outcome(s) Measured: Headache frequency was measured using a headache diary or calendar. A secondary objective included headache severity that was measured using a ten-point scale or …

Is Virtual Reality An Effective Tool For Reducing Procedural Pain In Pediatric Patients?, Rachel M. Wiegand

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this selective evidence-based medicine review is to determine whether or not, “Is virtual reality an effective tool for reducing procedural pain in pediatric patients?”

STUDY DESIGN: Included the review of three English language primary studies, published between 2014 and 2018. Articles were selected based on outcomes measured and relevance to the objective.

DATA SOURCES: PubMed was utilized to find two randomized controlled trials and one quasiexperimental study. The selected studies analyzed how the use of virtual reality impacted the amount of pain experienced by the pediatric patient undergoing either a venipuncture or burn wound care procedure. …

Is Topiramate Effective In Preventing Pediatric Migraines?, Krystina Zeliff

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this selective EBM review is to determine whether or not Topiramate is effective in the prevention of pediatric migraines.
Study Design: Review of three English language randomized control trials published in 2005, 2007, and 2009.

DATA SOURCES: Three double-blind, placebo-controlled, randomized trials comparing various doses of Topiramate to placebo were found using PubMed, OVID, and Cochrane Library databases.

OUTCOME(S) MEASURED: The frequency of migraines in patients under the age of 18 years old was documented with headache diaries. The patient’s parent would record the number, severity, duration, associated symptoms, and use of acute …

Is Allogeneic Stem Cell Transplantation Of High-Risk Pediatric Acute Lymphoblastic Leukemia (All) Patients More Effective In Preventing Future Relapses Of Disease And/ Or Mortality In Comparison With Chemotherapeutic Regimens Alone?, Patricia A. Ajizadeh

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this selective EBM review is to determine whether or not allogeneic SCT of HR pediatric ALL patients is more effective in preventing future relapses of disease and/or mortality in comparison with chemotherapeutic regimens alone.

STUDY DESIGN: Review of three English language primary randomized controlled trial studies published between 1996 and the present.

DATA SOURCES: Randomized controlled trial studies were found using PubMed.

OUTCOMES MEASURED: Each of the three studies evaluated the incidence of recurrent disease and/or mortality in high-risk pediatric ALL patients. These outcomes were analyzed according to the following categories: duration of event-free survival …