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Al-Azhar International Medical Journal
Abortion; Cervical ripening; misoprostol; Isosorbide mononitrate; (IMN)
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Second Trimester A Abortion Induction With Misoprostol Only Versus Misoprostol Plus Isosorbide Mononitrate: A Randomized Controlled Study, Emad Atalla
Al-Azhar International Medical Journal
Background: Efficacy of isosorbide mononitrate to reduce the interval of induction time in second trimester missed abortion . Aim of the study: To compare efficacy and safety of Isosorbide Mononitrate (IMN) and misoprostol for cervical ripening in second trimestric abortion. Patients and Methods: A randomized controlled prospective study was conducted. 160 patients aged between 18 & 35 years presenting with missed 2nd trimester abortion 13-26 wk gestation were included in this prospective clinical study. One group received only vaginal Misoprostol and the other group received combined vaginal Misoprostol with Isosorbide5-mononitrate. To determine the efficacy in form of (induction abortion interval) …