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Full-Text Articles in Medicine and Health Sciences

Side Effects And Efficacy Of Isotretinoin In College Students, Brittany Smith Jan 2020

Side Effects And Efficacy Of Isotretinoin In College Students, Brittany Smith

Mahurin Honors College Capstone Experience/Thesis Projects

Acne vulgaris is a serious disease that can have serious consequences for the person who has the condition. Acne can occur on the face, chest, back, and among other locations on the body. Its pathogenesis is complex and has many factors. Ahmad (2015), states acne involves abnormal keratinization, hormonal dysfunction and immune hypersensitivity. This condition can range from mild, moderate, or severe. Acne can be debilitating to the person who is struggling with it. Acne can occur at any age, but it is seen more often in adolescents. According to Marron, Tomas-Aragones, and Boira (2013), acne is prevalent in up …


A Look At Gene Control: Tracking The Ccnd1 Gene, Bryan Anders Jan 2020

A Look At Gene Control: Tracking The Ccnd1 Gene, Bryan Anders

Mahurin Honors College Capstone Experience/Thesis Projects

Cancer occurs when the cell does not properly control its own cell cycle. It then replicates in an out of control fashion leading to the death of various organs and then the demise of the organism as a whole. As it seems to have always been a problem for cell-based life, certain safeguards against cancer have been evolved over time. One such method comes in the form of prevention via cyclin proteins, which are encoded from cyclin genes. The gene that is the focus of this research is the CCND1, or cyclin D1, gene that controls the progression through various …


The Role Of Mitochondrial Pyruvate Carrier 1 (Mpc1) In Heart Failure And Its Implications For Cardiac Recovery, Obadiah Issachar Kirk Jan 2020

The Role Of Mitochondrial Pyruvate Carrier 1 (Mpc1) In Heart Failure And Its Implications For Cardiac Recovery, Obadiah Issachar Kirk

Mahurin Honors College Capstone Experience/Thesis Projects

Heart failure (HF) is a complex syndrome with high mortality rates around the world. HF also has diverse etiology as many things contribute such as hypertension, obesity, coronary artery disease, inflammation, and cardiac arrhythmias. Studies have shown that unloading of a failing heart with a left ventricular assist device (LVAD) can lead to cardiac recovery in a subpopulation of individuals with advanced HF. RNA-sequencing and protein expression analysis of myocardial tissue from HF patients who underwent the LVAD implant and heart transplant indicated that subpopulation of HF patients who responded to LVAD unloading had significantly lower levels of mitochondrial pyruvate …