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Medicine and Health Sciences Commons™

Open Access. Powered by Scholars. Published by Universities.®

Medical Specialties

Nova Southeastern University

2013

Articles 1 - 11 of 11

Full-Text Articles in Medicine and Health Sciences

Medical Education Digest, Vol. 15 No. 6 (November-December 2013), Nova Southeastern University Nov 2013

Medical Education Digest, Vol. 15 No. 6 (November-December 2013), Nova Southeastern University

Medical Education Digest

No abstract provided.

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Com Outlook Fall 2013, College Of Osteopathic Medicine Oct 2013

Com Outlook Fall 2013, College Of Osteopathic Medicine

COM Outlook

No abstract provided.

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Medical Education Digest, Vol. 15 No. 5 (September/October 2013), Nova Southeastern University Sep 2013

Medical Education Digest, Vol. 15 No. 5 (September/October 2013), Nova Southeastern University

Medical Education Digest

No abstract provided.

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Com Outlook Summer 2013, College Of Osteopathic Medicine Jul 2013

Com Outlook Summer 2013, College Of Osteopathic Medicine

COM Outlook

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Medical Education Digest, Vol. 15 No. 4 (July/August 2013), Nova Southeastern University Jul 2013

Medical Education Digest, Vol. 15 No. 4 (July/August 2013), Nova Southeastern University

Medical Education Digest

No abstract provided.

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Medical Education Digest, Vol. 15 No. 3 (May/June 2013), Nova Southeastern University May 2013

Medical Education Digest, Vol. 15 No. 3 (May/June 2013), Nova Southeastern University

Medical Education Digest

No abstract provided.

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Com Outlook Spring 2013, College Of Osteopathic Medicine Apr 2013

Com Outlook Spring 2013, College Of Osteopathic Medicine

COM Outlook

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Medical Education Digest, Vol. 15 No. 2 (March/April 2013), Nova Southeastern University Mar 2013

Medical Education Digest, Vol. 15 No. 2 (March/April 2013), Nova Southeastern University

Medical Education Digest

No abstract provided.

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Com Outlook Winter 2013, College Of Osteopathic Medicine Jan 2013

Com Outlook Winter 2013, College Of Osteopathic Medicine

COM Outlook

No abstract provided.

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Medical Education Digest, Vol. 15 No. 1 (January/February 2013), Nova Southeastern University Jan 2013

Medical Education Digest, Vol. 15 No. 1 (January/February 2013), Nova Southeastern University

Medical Education Digest

No abstract provided.

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Signaling Mechanisms Of Vav3, A Guanine Nucleotide Exchange Factor And Androgen Receptor Coactivator, In Physiology And Prostate Cancer Progression, Leah S. Lyons, Kerry L. Burnstein Jan 2013

Signaling Mechanisms Of Vav3, A Guanine Nucleotide Exchange Factor And Androgen Receptor Coactivator, In Physiology And Prostate Cancer Progression, Leah S. Lyons, Kerry L. Burnstein

Faculty Books and Book Chapters

The Rho GTPase guanine nucleotide exchange factor (GEF) Vav3 is the third member of the Vavfamily of GEFS and is activated by tyrosine phosphorylation. Through stimulation of Rho GTPaseactivity, Vav3 promotes cell migration, invasion, and other cellular processes. Work from our laboratory first established that Vav3 is upregulated in models of castration-resistant prostate cancer progression and enhances androgen receptor as well as androgen receptor splice variant activity. Recent analysis of clinical specimens supports Vav3 as a potential biomarker of aggressive prostate cancer. Consistent with a role in promoting castration-­resistant disease, Vav3 is a versatile enhancer of androgen receptor …

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