Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 1 of 1
Full-Text Articles in Medicine and Health Sciences
Treatment Of Metastatic Renal Cell Carcinoma, David J. Reeves, Chin Y. Liu
Treatment Of Metastatic Renal Cell Carcinoma, David J. Reeves, Chin Y. Liu
Scholarship and Professional Work – COPHS
Purpose
To review the treatment of metastatic renal cell carcinoma (RCC), including the use of new targeted therapies.
Methods
A search of MEDLINE (1966 to August 2008) and American Society of Clinical Oncology Meeting abstracts (2005 to May 2008) was preformed using the search terms bevacizumab, everolimus, interferon-alfa (IFN-α), interleukin-2 (IL-2), sorafenib, sunitinib, temsirolimus, and RCC. Articles most pertinent to the treatment of metastatic RCC are reviewed.
Results
The treatment of metastatic RCC has undergone a paradigm shift over the past 5 years from biologic response modifiers to new targeted therapies. Historically, response rates for the biological response modifiers, aldesleukin …