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The Role Of Physical Activity In Older Adults And Practical Intervention, Se Won Lee, Rebecca Patel, Bryan Werner, Ji Won Yoo, Timothy Tiu Dec 2021

The Role Of Physical Activity In Older Adults And Practical Intervention, Se Won Lee, Rebecca Patel, Bryan Werner, Ji Won Yoo, Timothy Tiu

HCA Healthcare Journal of Medicine

Physical inactivity (PI), defined as not meeting guidelines for physical activity beyond baseline daily living activities, is common among older adults (age 65 and older) and contributes to increased morbidity, increased mortality and increased health care spending. Understanding the clinical impact of PI on common medical conditions among older adults will help primary care physicians (PCPs) to educate these patients successfully. Physical activity and exercise are effective in the primary and secondary prevention of chronic diseases that can lead to physical impairments, disability and/or premature death. Physical activity and exercise have been shown to improve cognitive dysfunction and painful musculoskeletal …


The Effects Of Physical Activity On Cancer Patients Undergoing Treatment With Immune Checkpoint Inhibitors: A Scoping Review., Amy L Shaver, Swapnil Sharma, Nikita Nikita, Daniel S Lefler, Atrayee Basu-Mallick, Jennifer M Johnson, Meghan Butryn, Grace Lu-Yao Dec 2021

The Effects Of Physical Activity On Cancer Patients Undergoing Treatment With Immune Checkpoint Inhibitors: A Scoping Review., Amy L Shaver, Swapnil Sharma, Nikita Nikita, Daniel S Lefler, Atrayee Basu-Mallick, Jennifer M Johnson, Meghan Butryn, Grace Lu-Yao

Department of Medical Oncology Faculty Papers

BACKGROUND: Cancer therapies are associated with multiple adverse effects, including (but not limited to) cancer-related fatigue (CRF). Fatigue is one of the most common side effects of immune checkpoint inhibitors (ICIs), occurring in up to 25% of patients. Physical activity has been shown to help reduce CRF through modulating the immune system, and may synergistically aid in the anti-tumor effects of ICIs. This review describes the nature and scope of evidence for the effects associated with concurrent physical activity while undergoing ICI therapy.

METHOD: Scoping review methodology was utilized to identify studies, extract data, and collate and summarize results.

RESULTS: …


The Effects Of Physical Activity On Cancer Patients Undergoing Treatment With Immune Checkpoint Inhibitors: A Scoping Review, Amy L Shaver, Swapnil Sharma, Nikita Nikita, Daniel S Lefler, Atrayee Basu Mallick, Jennifer Johnson, Meghan Butryn, Grace Lu-Yao Dec 2021

The Effects Of Physical Activity On Cancer Patients Undergoing Treatment With Immune Checkpoint Inhibitors: A Scoping Review, Amy L Shaver, Swapnil Sharma, Nikita Nikita, Daniel S Lefler, Atrayee Basu Mallick, Jennifer Johnson, Meghan Butryn, Grace Lu-Yao

Department of Medical Oncology Faculty Papers

Background: Cancer therapies are associated with multiple adverse effects, including (but not limited to) cancer-related fatigue (CRF). Fatigue is one of the most common side effects of immune checkpoint inhibitors (ICIs), occurring in up to 25% of patients. Physical activity has been shown to help reduce CRF through modulating the immune system, and may synergistically aid in the anti-tumor effects of ICIs. This review describes the nature and scope of evidence for the effects associated with concurrent physical activity while undergoing ICI therapy.

Method: Scoping review methodology was utilized to identify studies, extract data, and collate and summarize results.

Results: …


Changes Of Exercise, Screen Time, Fast Food Consumption, Alcohol, And Cigarette Smoking During The Covid-19 Pandemic Among Adults In The United States, Liwei Chen, Jian Li, Tong Xia, Timothy A. Matthews, Tung-Sung Tseng, Lu Shi, Donglan Zhang, Zhuo Chen, Xuesong Han, Yan Li, Hongmei Li, Ming Wen, Dejun Su Sep 2021

Changes Of Exercise, Screen Time, Fast Food Consumption, Alcohol, And Cigarette Smoking During The Covid-19 Pandemic Among Adults In The United States, Liwei Chen, Jian Li, Tong Xia, Timothy A. Matthews, Tung-Sung Tseng, Lu Shi, Donglan Zhang, Zhuo Chen, Xuesong Han, Yan Li, Hongmei Li, Ming Wen, Dejun Su

School of Public Health Faculty Publications

Objective: To investigate the impact of the COVID-19 pandemic on multiple lifestyle changes among adults in the United States (USA). Methods: We conducted a survey, the Health, Ethnicity, and Pandemic (HEAP) Study, in October 2020 among USA adults. Participants were selected from the United States using 48 sampling strata, including age, race, ethnicity, education, and gender, and were asked to report five lifestyle behaviors (i.e., exercise time, screen time, fast-food meal consumption, alcohol drinking, and cigarette smoking) before and during the COVID-19 pandemic. The associations of sociodemographic factors with each lifestyle change were estimated using weighted multivariable logistic regression models. …


Community-Dwelling Older Adult Fall Prevention Improvement Project, Evan Edminster Bsn, Rn, Cfrn, Tcrn, Cen, Nhdp-Bc Aug 2021

Community-Dwelling Older Adult Fall Prevention Improvement Project, Evan Edminster Bsn, Rn, Cfrn, Tcrn, Cen, Nhdp-Bc

Master's Projects and Capstones

Abstract

Problem: Ground-level falls among community-dwelling adults 60 years and older are significant and contribute to adverse health outcomes such as fractures, functional decline, disability, and death. Additionally, falls among community-dwelling older adults are the number one mechanism of injury seen at a Northern California Level II trauma center. Falls often lead to post-fall fear, activity restriction, and physical deconditioning, further compounding fall risk.

Context: When trauma centers provide targeted outreach and screening for unmanaged health risks such as falls, they reduce unnecessary disability and premature death in the local population. Reducing total fall victim numbers and fall recidivism also …


What Is The Effect Of Physical Activity On The Reduction Of Macrovascular Complications In Patients Diagnosed With Type 2 Diabetes Mellitus?, Rachael M. Gordon Aug 2021

What Is The Effect Of Physical Activity On The Reduction Of Macrovascular Complications In Patients Diagnosed With Type 2 Diabetes Mellitus?, Rachael M. Gordon

Theses and Graduate Projects

The increasing prevalence and healthcare burden of type 2 diabetes is a worldwide concern. It is the seventh leading cause of mortality and a significant cause of morbidity. While both the macrovascular and microvascular complications of diabetes can have a profound impact on overall health and quality of life, cardiovascular events are the leading cause of mortality in patients with type 2 diabetes. Adults with diabetes have a two to four-fold increased risk of cerebrovascular events and myocardial infarctions. Oral medications combat insulin resistance and aid in the control of hemoglobin A1c, blood pressure, and cholesterol, therefore, contributing to a …


The Impacts Of Aging, Sedentarism, And Exercise On Neurotrophic Factor Expression And Innervation In The Heart And The Effects Of Treatment With Α-Cgrp On Heart Function, Gabriel Almeida Alves Aug 2021

The Impacts Of Aging, Sedentarism, And Exercise On Neurotrophic Factor Expression And Innervation In The Heart And The Effects Of Treatment With Α-Cgrp On Heart Function, Gabriel Almeida Alves

Dissertations

Neurotrophic factors (NFs) are important molecules responsible for development, differentiation, regeneration, and maintenance of new and mature neurons. Neurotrophic factors act as neurocytokines and may assist with the regulation of axonal and dendritic arrangements and synaptic plasticity between neurons themselves or with other non-neural target tissues. In this study, we analyze the levels of two NFs: glial cell line-derived neurotrophic factor (GDNF) and nerve growth factor (NGF). Cardiomyocytes produce these neurotrophic factors which assist with the innervation pattern of the heart. The heart is innervated by the two branches of the autonomic nervous system; namely the sympathetic nervous system and …


Returning To Sport: Female Athletes Living With And Beyond Cancer., Anna L. Schwartz, Christopher Terry Aug 2021

Returning To Sport: Female Athletes Living With And Beyond Cancer., Anna L. Schwartz, Christopher Terry

Kimmel Cancer Center Faculty Papers

Many athletes living with and beyond cancer can continue to train and, in some cases, compete during treatment. Following cancer treatment, athletes can return to competitive sport but need to learn to adapt their physical strength and training to the lingering effects of cancer. It is critical for oncology healthcare providers to use the principles of assess, refer and advise to exercise oncology programs that are appropriate for the individual. Managing side effects of treatment is key to being able to train during and immediately following cancer treatment. Keen attention to fatigue is important at any point in the cancer …


Does Exercise Prevent Gestational Diabetes Mellitus In Pregnant Women? A Clin-Iq, Olivia Lust, Tana Chongsuwat, Elizabeth Lanham, Ann F. Chou, Elizabeth Wickersham Jul 2021

Does Exercise Prevent Gestational Diabetes Mellitus In Pregnant Women? A Clin-Iq, Olivia Lust, Tana Chongsuwat, Elizabeth Lanham, Ann F. Chou, Elizabeth Wickersham

Journal of Patient-Centered Research and Reviews

Excessive weight gain during pregnancy has been on the rise globally, leading to increased prevalence of gestational diabetes mellitus (GDM). A diagnosis of GDM often leads to pregnancy and infant-related complications. Regular exercise may have the potential to prevent GDM. However, evidence surrounding the utility of exercise during pregnancy as an effective risk reduction intervention has been mixed. This clinical inquiry examined the role of regular exercise during pregnancy in preventing GDM in both obese and normal-weight women and analyzed specific aspects of exercise that make it an effective preventive measure. The review of evidence included 3 meta-analyses, 3 systematic …


Physical Activity Interventions For Older Adults In The Age Of Covid-19 And Beyond, Rachel N. Bragg, K. Jason J. Crandall May 2021

Physical Activity Interventions For Older Adults In The Age Of Covid-19 And Beyond, Rachel N. Bragg, K. Jason J. Crandall

Topics in Exercise Science and Kinesiology

Topics in Exercise Science and Kinesiology Volume 2: Issue 1, Article 6, 2021. As the coronavirus (COVID-19) pandemic continues, it is important to understand why older adults are at higher risk for more severe morbidity and higher mortality compared to younger age groups. At the same time, there is a growing body of evidence suggesting physical activity and exercise can have positive benefits for older adults’ health. Point of application #1: The first step in keeping older adults active is motivating them to adhere to a structured program either at home, in a community setting, or in a long-term care …


The Impact Of Exercise On Pregnant Women Aged 18-40 And Fetal Development, Jinisha Patwa May 2021

The Impact Of Exercise On Pregnant Women Aged 18-40 And Fetal Development, Jinisha Patwa

Rowan-Virtua Research Day

68% of those who performed minimum level exercise prior to pregnancy stopped completely during early pregnancy.

Women stop exercising during pregnancy due to worries about the impact it may have on the development of the fetus.

Starting moderate-intensity, weight-bearing exercise early in pregnancy increases placental growth rate and volume.

Exercise reduces the risks of excess gestational weight gain and high maternal body weight before pregnancy.

Physical exercise reduces the risk of gestational diabetes mellitus.


Exercise-Induced Alterations In Phospholipid Hydrolysis, Airway Surfactant, And Eicosanoids And Their Role In Airway Hyperresponsiveness In Asthma, Ryan C Murphy, Ying Lai, James D Nolin, Robier A Aguillon Prada, Arindam Chakrabarti, Michael V Novotny, Michael C Seeds, William A Altemeier, Michael H Gelb, Robert Duncan Hite, Teal S Hallstrand May 2021

Exercise-Induced Alterations In Phospholipid Hydrolysis, Airway Surfactant, And Eicosanoids And Their Role In Airway Hyperresponsiveness In Asthma, Ryan C Murphy, Ying Lai, James D Nolin, Robier A Aguillon Prada, Arindam Chakrabarti, Michael V Novotny, Michael C Seeds, William A Altemeier, Michael H Gelb, Robert Duncan Hite, Teal S Hallstrand

Journal Articles

The mechanisms responsible for driving endogenous airway hyperresponsiveness (AHR) in the form of exercise-induced bronchoconstriction (EIB) are not fully understood. We examined alterations in airway phospholipid hydrolysis, surfactant degradation, and lipid mediator release in relation to AHR severity and changes induced by exercise challenge. Paired induced sputum (


The Study Of High Intensity Interval Training's Effect On Enjoyment, Keali Mari May 2021

The Study Of High Intensity Interval Training's Effect On Enjoyment, Keali Mari

Theses/Capstones/Creative Projects

This study assessed participant’s level of enjoyment in high-intensity training over moderate intensity-training. High intensity interval training is defined as short bouts of exercise performed at a near-maximal effort with rest periods or light activity in between. High intensity interval training involves repeatedly exercising at a high intensity for 30 seconds to several minutes, separated by 1-5 minutes of recovery. This type of exercise has sparked the interest of many active people due to its decreased time commitment and the benefits it elicits. The results of this study show that high intensity interval training induces a higher enjoyment rate pre- …


Resources For Staying Active During The Covid-19 Pandemic, Peter K. Twining Jan 2021

Resources For Staying Active During The Covid-19 Pandemic, Peter K. Twining

Family Medicine Clerkship Student Projects

During the COVID-19 pandemic, many patients find it difficult to stay active. Staying active when gyms are closed and school sports are cancelled can make staying active especially difficult. The purpose of this project was to compile a list of resources for patients to use to stay active and healthy at home during the pandemic.


Inclusive Local And Online Resources To Stay Active During The Covid-19 Pandemic, Collin B. Montgomery Jan 2021

Inclusive Local And Online Resources To Stay Active During The Covid-19 Pandemic, Collin B. Montgomery

Family Medicine Clerkship Student Projects

The COVID-19 pandemic has interrupted daily life in an innumerable amount of ways. Through gym closures and overcrowded, unsafe public spaces, maintaining exercise routines and reaching physical activity recommendations is increasingly difficult for many people. As a result of this, there has been an increasing emphasis on at home exercise and routines people can do at home. However, many of these resources are not inclusive of populations such as the elderly, people with disabilities, and the otherwise deconditioned as the exercises can be too strenuous or require specific equipment. The goal of this project was to compile a list of …


Exercise As A Tool For Treating Anxiety And Depression, Lizzi Hahn Jan 2021

Exercise As A Tool For Treating Anxiety And Depression, Lizzi Hahn

Family Medicine Clerkship Student Projects

In addition to its important role in the maintenance of physical health, exercise has been shown to have numerous benefits for mental health. Recent studies indicate that even brief engagement in physical activity can make a positive impact on the treatment of pre-existing anxiety and depression - as well as the prevention of future symptoms. Despite this relationship between exercise and emotional wellness, regular activity in the United States is still exceedingly low, and exercise remains an underused tool by healthcare providers in the treatment of their patients’ anxiety and depression. The goal of this project was to assess patient …


Frequently Asked Questions By Patients About Exercise, Julie Evans Jan 2021

Frequently Asked Questions By Patients About Exercise, Julie Evans

Family Medicine Clerkship Student Projects

A significant portion of patient visits at Milton Family Practice are related to one or multiple aspects of metabolic syndrome. Exercise is a common topic during these visits either brought up by patients or providers. This project focused on creating a handout for patient education with answers to commonly asked questions pertaining to exercise and resources in the community.


Remaining Active In Vermont Winters, Sarah Kendrick Jan 2021

Remaining Active In Vermont Winters, Sarah Kendrick

Family Medicine Clerkship Student Projects

This project explored the challenges of remaining active during Vermont winter for patients with chronic disease. It further complies resources in the community for maintaining activity levels over the winter months.


Addressing Exercise And Physical Therapy In Older Patients In Colchester, Vt, Adam Morehead Jan 2021

Addressing Exercise And Physical Therapy In Older Patients In Colchester, Vt, Adam Morehead

Family Medicine Clerkship Student Projects

Participation in physical activities remains low among much of the older adult population, particularly during the winter months. Many individuals who are active during warmer times of the year become more sedentary during the winter, and this physical inactivity can contribute to declining health. This project sought to develop a simple brochure outlining several simple exercises that can be performed safely at home without equipment to be distributed to patients at wellness visits to encourage indoor exercise.


Smoking Cessation Associated Weight Gain: The Role Of Diet And Exercise Counseling In Quitting Smoking, Benjamin D. Kagan Jan 2021

Smoking Cessation Associated Weight Gain: The Role Of Diet And Exercise Counseling In Quitting Smoking, Benjamin D. Kagan

Family Medicine Clerkship Student Projects

Weight gain is a common unintended consequence of quitting smoking due to a combination of physiologic and behavioral factors. Counseling focused on diet and exercise reduces weight gain associated with smoking cessation. Reduction of weight gain related to smoking cessation maximizes the health benefit of quitting tobacco.


Low-Cost At-Home Cardio Solutions For Patients During The Covid-19 Pandemic, Anna G. Quinlan Jan 2021

Low-Cost At-Home Cardio Solutions For Patients During The Covid-19 Pandemic, Anna G. Quinlan

Family Medicine Clerkship Student Projects

No abstract provided.


Helping People Overcome Barriers To Exercise Through In-Office Pt Exercise Evaluation Referrals, Matthew Charles Hill Brandt Jan 2021

Helping People Overcome Barriers To Exercise Through In-Office Pt Exercise Evaluation Referrals, Matthew Charles Hill Brandt

Family Medicine Clerkship Student Projects

Utilization of a poster in a primary care exam room advertising Physical Therapy Exercise Evaluations in an effort to help patients overcome barriers to exercising. The goal of the project is to capture people in the contemplative/preparatory stage of behavior change and help them reach the action and maintenance phases to improve health.


Addressing Rational Barriers To Lifestyle And Behavioral Modification, Ahmed Eldakroury Jan 2021

Addressing Rational Barriers To Lifestyle And Behavioral Modification, Ahmed Eldakroury

Family Medicine Clerkship Student Projects

Rational barriers contribute to resistance towards initiating, restarting or maintaining lifestyle/behavioral modification. Such barriers include lack of confidence in the proposed intervention(s), exaggerated perspectives, unsubstantiated beliefs and feelings of futility/hopelessness in the setting of past failures or relapse. Lifestyle and behavioral modification are core elements of preventative health and mental health—identifying and addressing erroneous thought processes, perspectives or beliefs that contribute to hesitancy may empower patients to trust the process and put an honest effort towards making those changes. Thus, a motivational pamphlet was created for patients with the goal of addressing hesitancy/resistance towards initiating or maintaining lifestyle/behavioral modification. The …


Walking Towards A Healthier Future: A Pocket Guide To Walking Routes In Colchester And The Health Benefits Of Walking, Kevin Dibona Jan 2021

Walking Towards A Healthier Future: A Pocket Guide To Walking Routes In Colchester And The Health Benefits Of Walking, Kevin Dibona

Family Medicine Clerkship Student Projects

The obesity epidemic is a complex problem necessitating a multifaceted long-term response. While there is no single solution to this decade-evolving issue, exercise remains one of the most important health interventions available. This project aims to serve as a resource for patients seeking to lose weight; outlining some of the walking routes local to Colchester Vermont, as well as the health benefits of a sustained exercise plan.