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Full-Text Articles in Medicine and Health Sciences
A Method For Predicting Dose Changes For Hn Treatment Using Surface Imaging, Sarah E. Holler
A Method For Predicting Dose Changes For Hn Treatment Using Surface Imaging, Sarah E. Holler
Theses and Dissertations
Head and neck cancer is commonly treated with a six- to seven-week course of radiotherapy, during which a patient’s anatomy may change substantially, due to target reduction or weight loss. Anatomical changes lead to reduction in treatment quality due to decreased setup reproducibility and altered dose deposition compared to the original plan. Few clinics have developed a standard method for triggering resimulation and replan due to anatomic changes. This work investigates a new method for determining when to resimulate and replan HNC patients by utilizing their topographic anatomical changes to predict differences in planned versus delivered dose distributions. The first …
An Investigation Of Nurbs-Based Deformable Image Registration, Travis J. Jacobson
An Investigation Of Nurbs-Based Deformable Image Registration, Travis J. Jacobson
Theses and Dissertations
Deformable image registration (DIR) is an essential tool in medical image processing. It provides a means to combine image datasets, allowing for intra-subject, inter-subject, multi-modality, and multi-instance analysis, as well as motion detection and compensation. One of the most popular DIR algorithms models the displacement vector field (DVF) as B-splines, a sum of piecewise polynomials with coefficients that enable local shape control. B-splines have many advantageous properties in the context of DIR, but they often struggle to adequately model steep local gradients and discontinuities. This dissertation addresses that limitation by proposing the replacement of conventional B-splines with a generalized formulation …