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Subanesthetic Ketamine For Postoperative Analgesia: An Evidenced-Based Project, Jeremy Vance Dec 2017

Subanesthetic Ketamine For Postoperative Analgesia: An Evidenced-Based Project, Jeremy Vance

Doctoral Projects

Roughly 100 million surgical procedures are performed in the United States (U.S.) each year and more than 80% of these patients experience acute postoperative pain. Pain costs the U.S. an estimated $560 to $635 billion annually and is a significant contributor to national rates of mortality, morbidity, and disability. Despite these findings, patients continue to receive suboptimal postoperative pain relief.

The adjunct administration of subanesthetic ketamine is opioid-sparing and can improve the effectiveness of a multimodal pain management approach. This project used an exploratory descriptive design to examine how an evidence-based presentation impacted the clinical practice of certified registered nurse …


Motor Learning And Adaptation In People With Knee Osteoarthritis And Chronic Pain, Heather Turcotte, Katherine S. Rudolph Jul 2017

Motor Learning And Adaptation In People With Knee Osteoarthritis And Chronic Pain, Heather Turcotte, Katherine S. Rudolph

Osteopathic Medicine Student Research Posters

Osteoarthritis (OA) affects an estimated 50 million people in the US, and approximately 43% have limitations in daily function due to arthritis pain.3 Individuals with knee osteoarthritis (OA) have heightened sensitization to pain2,5 as well as reduced strength, diminished function and quality of life1 that prompts them to seek care from health care providers. Physical therapists commonly work with patients to improve function and quality of life by helping them learn to move without pain. Unfortunately, chronic pain causes changes to the nervous system that may impact the ability to learn new ways but the extent to which chronic pain …


Sex-Related Differences In The Efficacy Of Dexamethasone Pretreatmentfor Postoperative Analgesia In Patients Undergoing Laparoscopiccholecystectomy: A Randomized Controlled Study, Choel Lee, Jae-Yoon Chung, Myeongjong Lee Jan 2017

Sex-Related Differences In The Efficacy Of Dexamethasone Pretreatmentfor Postoperative Analgesia In Patients Undergoing Laparoscopiccholecystectomy: A Randomized Controlled Study, Choel Lee, Jae-Yoon Chung, Myeongjong Lee

Turkish Journal of Medical Sciences

Background/aim: Sex-related differences in response to pain have become a topic of increasing interest. However, sex-related differences in the efficacy of dexamethasone for postoperative analgesia have not been previously addressed. Materials and methods: The study included 196 men and 196 women, aged between 18 and 45 years, who were scheduled for laparoscopic cholecystectomy. The patients were randomly allocated into dexamethasone (M/F: 98/98) and control (normal saline; M/F: 98/98) groups. Patients in the study group received intravenous dexamethasone at 0.1 mg/kg (dexamethasone group) 1 h before induction of anesthesia. Patients in the control group received normal saline. Changes in cumulative morphine-containing, …


The Effect Of Acute Pain On Executive Function, Jenna M. Morogiello Jan 2017

The Effect Of Acute Pain On Executive Function, Jenna M. Morogiello

Electronic Theses and Dissertations

Background: Executive functions are high-level cognitive processes that allow a person to successfully engage in an independent and self-fulfilling life. Previous literature indicates that acute pain can affect executive function, which may be due to a limited amount of shared neural resources of the brain.

Objective: The purpose of this study was to determine if acute pain affects executive function in recreationally active individuals who sustain a musculoskeletal injury.

Methodology: Twenty-four participants who presented with acute pain due to a musculoskeletal injury underwent a neuropsychological battery within 72 hours of injury and within two weeks from the initial testing session. …