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Full-Text Articles in Medicine and Health Sciences
Embryonic Stem Cell Derived Neural Precursor Grafts For Treatment Of Temporal Lobe Epilepsy, Janice R. Naegele
Embryonic Stem Cell Derived Neural Precursor Grafts For Treatment Of Temporal Lobe Epilepsy, Janice R. Naegele
Janice R Naegele
Temporal Lobe Epilepsy (TLE). For many TLE patients, there is an initial traumatic head injury that is the precipitating cause of epilepsy. Severe TLE can be associated with neuropathological changes, including hippocampal sclerosis, neurodegeneration in the dentate gyrus, and extensive reorganization of hippocampal circuits. Learning disabilities and psychiatric conditions may also occur in patients with severe TLE for whom conventional anti-epileptic drugs are ineffective. Novel treatments are needed to limit or repair neuronal damage, particularly to hippocampus and related limbic regions in severe TLE and to suppress temporal lobe seizures. A promising therapeutic strategy may be to restore inhibition of …
Gene And Stem Cell Therapies For Treating Epilepsy., Janice Naegele, Xu Maisano
Gene And Stem Cell Therapies For Treating Epilepsy., Janice Naegele, Xu Maisano
Janice R Naegele
No abstract provided.
Trekking Through The Telencephalon: Hepatocyte Growth Factor-Mediated Guidance For Parvalbumin-Expressing Interneurons, Janice R. Naegele
Trekking Through The Telencephalon: Hepatocyte Growth Factor-Mediated Guidance For Parvalbumin-Expressing Interneurons, Janice R. Naegele
Janice R Naegele
No abstract provided.