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Toxicity Of Flow Line, Durafill Vs, And Dycal To Dental Pulp Cells: Effects Of Growth Factors, Alyssa Furey, Julie Hjelmhaug, Doug Lobner
Toxicity Of Flow Line, Durafill Vs, And Dycal To Dental Pulp Cells: Effects Of Growth Factors, Alyssa Furey, Julie Hjelmhaug, Doug Lobner
Biomedical Sciences Faculty Research and Publications
Introduction
The objective was to determine the effects of growth factor treatment on dental pulp cell sensitivity to toxicity of 2 composite restoration materials, Flow Line and Durafill VS, and a calcium hydroxide pulp capping material, Dycal.
Methods
Toxicity of the dental materials to cultures of primary dental pulp cells was determined by the MTT metabolism assay. The ability of 6 different growth factors to influence the toxicity was tested.
Results
A 24-hour exposure to either Flow Line or Durafill VS caused approximately 40% cell death, whereas Dycal exposure caused approximately 80% cell death. The toxicity of Flow Line and …