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Full-Text Articles in Medicine and Health Sciences
Biochemical And Molecular Characterization Of The Prostate-Specific Membrane Antigen (Psma), John Karl Troyer
Biochemical And Molecular Characterization Of The Prostate-Specific Membrane Antigen (Psma), John Karl Troyer
Theses and Dissertations in Biomedical Sciences
Prostate cancer is the most common malignancy and the second leading cause of cancer death in males in the United States. Additionally, the number of deaths attributed to prostate cancer is increasing at a rate of approximately 8% a year. Development of new diagnostic and therapy strategies are needed in order to improve the life expectancy of patients with this disease. One tool which may allow for improvements in prostate cancer diagnosis and therapy is the monoclonal antibody (MAb) 7E11-C5.3 which was first described in 1987. Since then, the antigen recognized by MAb 7E11-C5.3 has been named the prostate specific …
Modulation Of Neutrophil Functions By Neurotransmitters Implicated In Stress, Chok Ping Wan
Modulation Of Neutrophil Functions By Neurotransmitters Implicated In Stress, Chok Ping Wan
Loma Linda University Electronic Theses, Dissertations & Projects
Stress has long been implicated in immune modulation. People under chronic stress have no change in the circulating basal levels of catecholamines while plasma levels of neuropeptide Y (NPY) are significantly increased. Sympathetic nerve fibers with NPY have been found to innervate immune organs. It was hypothesized that NPY might be a mediator in immune modulation in people under chronic stress. Human neutrophils were used as a model to study the effects of NPY alone or together with norepinephrine on the immune system. We now report that NPY modulates oxidative burst (OB) triggered by zymosan in human neutrophils while it …
A Model Of Cytomegalovirus Association With The Development Of Heart Graft Atherosclerosis, Evan Skowronski
A Model Of Cytomegalovirus Association With The Development Of Heart Graft Atherosclerosis, Evan Skowronski
Loma Linda University Electronic Theses, Dissertations & Projects
The development of graft atherosclerosis in heart transplant recipients has been associated with the development of post-transplant cytomegalovirus infection. The mechanism of this involvement, however, remains unclear. I undertook a study to determine the role of cytomegalovirus in the development of graft atherosclerosis. First, a rapid method of detecting cytomegalovirus based on capillary polymerase chain reaction and gel electrophoresis was employed to determine the presence of cytomegalovirus in a wide variety of clinical samples. Detection of cytomegalovirus is a lengthy procedure under normal conditions, and timely detection of cytomegalovirus in transplant recipients may allow intervention early enough to block the …
Effectiveness Of Dna Probe Technology In Distinguishing Among Gingival Health, Mild-Moderate Periodontitis, And Severe Periodontitis In Human Oral Sites, Juliana J. Kim
Dental Hygiene Theses & Dissertations
The purpose of this investigation was to determine if there is a difference in the type of microorganisms found in oral sites classified as gingival health, mild-moderate periodontitis, or severe periodontitis as measured by the DMDx* Test. A purposive sample of one hundred oral sites was selected from adult patients. Subjects were excluded from the study based on: the presence of any systemic disorders, communicable diseases, diabetic conditions, blood dyscrasias, congenital heart disease, rheumatic heart disease, pregnancy, history of periodontal surgery, prosthetic joint replacement, hypertensive heart disease, or any medications that might alter the gingival tissues (e.g. antibiotics, hormonal therapy, …
Characterization Of The On And Off Pathways In Human Vision, Luisa Roveri
Characterization Of The On And Off Pathways In Human Vision, Luisa Roveri
Master's Theses
No abstract provided.
Pharmacokinetics And Pharmacodynamics Of Recombinant Hirudin Variant 2 (Rhv2) In Animal Models, Lalitha Iyer
Pharmacokinetics And Pharmacodynamics Of Recombinant Hirudin Variant 2 (Rhv2) In Animal Models, Lalitha Iyer
Dissertations
No abstract provided.