Medicine and Health Sciences Commons^™

Survival Benefit Of Resin Cartridge Extracorporeal Blood Purification Therapy In Patients With Septic Shock, Serdar Efe, Pervin Hanci, Volkan İnal

Turkish Journal of Medical Sciences

Extracorporeal blood purification (EBP) therapies have shown promise as potential rescue treatments for patientswith septic shock. However, precise evidence regarding their effectiveness is lacking. This case-control study aimed to evaluate the 28-day survival benefit of a resin cartridge-based EBP therapy compared to conventional therapies in patients with septic shock.Materials and methods: The study sample was collected retrospectively from the medical records of patients admitted to the intensivecare unit (ICU) between 2015 and 2020. The study included patients with septic shock aged ≥18 years who had ICU stays >96 h andexcluded those lost to follow-up by 28 days or readmitted. First, …

C-Reactive Protein In View Of Prognosis In Sepsis, Ashraf A.H Mahmoud Soliman, Raghad S. Abdellatif, Wael A. E. El Hakeem

Journal of Medicine in Scientific Research

Introduction Sepsis is the host reaction to invading microbes. The septic response generally occurs when immune defenses fail to contain an invading microbe and may also be induced by microbial exotoxins. C-reactive protein (CRP) is an acute-phase protein in humans and an important component of the innate immune system. CRP activates complement's classical route, which is one of its key strategies for defending the host. Patients and methods This study was conducted on 20 patients with systemic sepsis and admitted to the critical care unit; moreover, 20 healthy participants were studied as a control group. Results Both groups were matched …

Methamphetamine Associated Cardiomyopathy In Pregnancy: The Distinctions And The Implications, Ashan Hatharasinghe, Hossein Akhondi

HCA Healthcare Journal of Medicine

Introduction

Methamphetamine associated cardiomyopathy (MAC) and peripartum cardiomyopathy (PPCM) are both rare obstetric conditions. Literature regarding methamphetamine associated cardiomyopathy in the obstetric population is limited, and it can be difficult to make the distinction between the two given the similarities in clinical presentation. However similar, there are significant distinctions in the pathophysiology of these two that can help clinicians with the management process.

Clinical Findings and Outcomes

This case involves a 35-year-old Hispanic G6P5005 at 37 weeks gestation presenting with acute respiratory failure secondary to acute decompensated heart failure with reduced ejection fraction and superimposed preeclampsia leading to urgent cesarean …

Esophageal Cancer Complicated By A Distal Acquired Esophagopulmonary Fistula, Alexander D. Lake, Yousef Almuzaini, Aaron Jaffe, Joseph Staffetti, Mukesh Patel

HCA Healthcare Journal of Medicine

Esophageal respiratory fistulas, commonly found as a tracheoesophageal fistula (TEF), are abnormal connections between the esophagus and trachea. These can be congenital (infants) or acquired (malignancy). A more rare form of an esophageal respiratory fistula is an abnormal connection between the esophagus and the lung parenchyma—also known as an esophagopulmonary fistula. In our case, we present a middle-aged male with a history of esophageal cancer undergoing chemotherapy and radiation presenting into the intensive care unit for increasing shortness of breath and vomiting after eating found to have a rare form of a TEF causing his symptoms.

Emergency Department Extracorporeal Membrane Oxygenation May Also Includenoncardiac Arrest Patients, Yunus Emre Özlüer, Mücahi̇t Avci̇l, Duygu Ege, Kezban Şeker Yaşar

Turkish Journal of Medical Sciences

Background/aim: The primary purpose of this study is to report the experience on the extracorporeal membrane oxygenation (ECMO) process for patients in the critical care unit (CCU) of an emergency department of a tertiary hospital in Turkey, from cannulation to decannulation, including follow-up procedures. Materials and methods: This retrospective and observational study included eight patients who received ECMO from January 2018 to January 2020. We evaluated the demographics, indications for ECMO, laboratory values, Respiratory ECMO Survival Prediction, Survival After Veno-Arterial ECMO and ECMO net scores, the management process, and patient outcomes. Blood gas analyses done after the first hour of …

Clinical Characteristics And Risk Factors For 28-Day Mortality In Critically Ill Patients With Covid-19: A Retrospective Cohort Study, Mehmet Nuri̇ Yakar, Begüm Ergan, Bi̇şar Ergün, Murat Küçük, Ali̇ Cantürk, Mahmut Cem Ergon, Naci̇ye Si̇nem Gezer, Erdem Yaka, Bi̇lgi̇n Cömert, Ali̇ Necati̇ Gökmen

Turkish Journal of Medical Sciences

Background: To date, the coronavirus disease 2019 (COVID-19) caused more than 2.6 million deaths all around the world. Risk factors for mortality remain unclear. The primary aim was to determine the independent risk factors for 28-day mortality. Materials and Methods: In this retrospective cohort study, critically ill patients (≥ 18 years) who were admitted to the intensive care unit due to COVID-19 were included. Patient characteristics, laboratory data, radiologic findings, treatments, and complications were analyzed in the study. Results: A total of 249 patients (median age 71, 69.1% male) were included in the study. 28-day mortality was 67.9% (n = …

Value Of Prognostic Scores In Antineutrophil Cytoplasmic Antibody (Anca) Associated Vasculitis Patients In Intensive Care Unit: A Multicenter Retrospective Cohort Study From Turkey, Uğur Özdemi̇r, Nazmi̇ye Ebru Ortaç Ersoy, Recep Ci̇van Yüksel, Erhan Kaya, Şahender Gülbi̇n Aygencel Bikmaz, Melda Türkoğlu, Arzu Topeli̇ İski̇t, Muhammet Güven, Murat Sungur, Neri̇man Defne Altintaş

Turkish Journal of Medical Sciences

Background/aim: There is a need for a scoring system for predicting ICU prognosis of patients with ANCA-associated vasculitis (AAV), but there are limited data on it in the literature. Therefore, we aimed to determine the scores that can estimate the prognosis of patients with AAV during intensive care follow up.Materials and methods: All adult patients admitted to the medical ICUs of 4 reference university hospitals in Turkey due to AAV activation and/or disease/treatment complications in the last 10 years were included in this study. Demographic data, treatments before ICU, the Birmingham Vasculitis Activity Score (BVAS) score at the time of …

Can We Predict Patients That Will Not Benefit From Invasive Mechanical Ventilation? A Novel Scoring System In Intensive Care: The Imv Mortality Prediction Score (Impres), Tevfi̇k Özlü, Mehtap Pehli̇vanlar Küçük, Akin Kaya, Esra Yarar, Sami̇ Cenk Kirakli, Özlem Şengören Di̇ki̇ş, Hale Kefeli̇ Çeli̇k, Serdar Özkan, Hayri̇ye Bektaş Aksoy, Ahmet Oğuzhan Küçük

Turkish Journal of Medical Sciences

Background/aim: The present study aimed to define the clinical and laboratory criteria for predicting patients that will not benefit from invasive mechanical ventilation (IMV) treatment and determine the prediction of mortality and prognosis of these critical ill patients. Materials and methods: The study was designed as an observational, multicenter, prospective, and cross-sectional clinical study. It was conducted by 75 researchers at 41 centers in intensive care units (ICUs) located in various geographical areas of Turkey. It included a total of 1463 ICU patients who were receiving invasive mechanical ventilation (IMV) treatment. A total of 158 parameters were examined via logistic …

Mortality Predictors Of Patients Suffering Of Acute Pancreatitis And Development Of Intraabdominal Hypertension, Maja Stojanovic, Petar Svorcan, Aleksandar Karamarkovic, Nebojsa Ladjevic, Radmilo Jankovic, Predrag Stevanovic

Turkish Journal of Medical Sciences

Background/aim: Intraabdominal hypertension (IAH) occurs frequently in patients with acute pancreatitis and adds to their morbidity and mortality. The main aim of the study was to identify the determination of the predictive factors connected to IAH that influence the evolution of acute pancreatitis. Materials and methods: The prospective cohort study was conducted on 100 patients who had acute pancreatitis. According to obtained intraabdominal pressure (IAP) values, the patients were divided into two groups: one group (n = 40) with normal IAP values and the other (IAH group, n = 60) with increased IAP values. Deceased patients were specially analyzed within …

The Incidence Of Pressure Ulcer In Patients On Mechanical Ventilation Andeffects Of Selected Risk Factors On Pressure Ulcer Development*, Özgül Karayurt, Özay Akyol, Necmi̇ye Kiliçaslan, Nuray Akgün, Ümran Sargin, Meli̇ke Kondakçi, Hanim Eki̇nci̇, Nesli̇han Sari

Turkish Journal of Medical Sciences

Background/aim: This study aimed to determine the incidence of pressure ulcers in patients on mechanical ventilation and selected risk factors likely to play a role in pressure ulcer development. Materials and methods: The study included 110 patients recruited from an anesthesia critical care unit of a university hospital. Data were collected with a demographic and clinical characteristics form. The form was composed of questions about demographic characteristics and clinical features including diagnosis, duration of mechanical ventilation, general well-being, oxygenation, perfusion, and skin condition. Results: The incidence of pressure ulcer was 15.5%. Duration of mechanical ventilation was longer and the body …