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Full-Text Articles in Medicine and Health Sciences
The Efficacy And Safety Of Targeted Narrowband Uvb Therapy: A Retrospective Cohort Study, Kübra Esen Salman, İlknur Altunay, Andaç Salman
The Efficacy And Safety Of Targeted Narrowband Uvb Therapy: A Retrospective Cohort Study, Kübra Esen Salman, İlknur Altunay, Andaç Salman
Turkish Journal of Medical Sciences
Background/aim: Phototherapy is a safe and effective treatment modality for numerous dermatological conditions. Recently, targeted phototherapy modalities have gained importance due to their advantages over conventional phototherapy.This retrospective study aimed to evaluate the safety and efficacy of targeted narrowband UVB phototherapy in patients with dermatological disorders.Materials and methods: This single-center study included 173 patients who were treated with targeted narrowband UVB phototherapy. Demographic features, phototherapy parameters, and adverse effects were evaluated in all patients, and the treatment response was assessed in patients who attended at least one follow-up visit. Results: A total of 173 patients (102 females; 71 males) with …
Assessment Of Cardiac And Vessel Functions In Childhood Psoriasis, Berna Şaylan Çevi̇k, Fi̇gen Akalin, Eli̇f Erolu, Di̇lek Seçki̇n Gençosmanoğlu, Safi̇ye Atlas Tüli̇n Ergun
Assessment Of Cardiac And Vessel Functions In Childhood Psoriasis, Berna Şaylan Çevi̇k, Fi̇gen Akalin, Eli̇f Erolu, Di̇lek Seçki̇n Gençosmanoğlu, Safi̇ye Atlas Tüli̇n Ergun
Turkish Journal of Medical Sciences
Background/aim: Psoriasis is a chronic inflammatory disease. The effect of psoriasis on the cardiovascular system has not been studied in children before. We studied ventricular strain and vascular functions to assess early cardiovascular effects of psoriasis during childhood. Materials and methods: The study population consisted of 20 psoriatic and 20 age- and sex-matched control subjects. Two-dimensional echocardiography images, longitudinal and global strain, and carotid and brachial ultrasound studies were performed. Results: The mean age of psoriatic children was 14 ± 0.89 years and that of the controls was 14.05 ± 0.88. There were significant increases in terms of interventricular septum …
Investigation Of Oxidant And Antioxidant Levels In Patients With Psoriasis, Okan Kizilyel, Necmetti̇n Akdeni̇z, Mahmut Sami̇ Meti̇n
Investigation Of Oxidant And Antioxidant Levels In Patients With Psoriasis, Okan Kizilyel, Necmetti̇n Akdeni̇z, Mahmut Sami̇ Meti̇n
Turkish Journal of Medical Sciences
Background/aim: Psoriasis is an immune-mediated chronic inflammatory skin disease that is seen in 1%?3% of the population. It is characterized by symmetrical papulosquamous lesions on the scalp, knees, elbows, sacral region, and extensor surfaces of the extremities. Psoriasis affects both sexes equally. It is thought that reactive oxygen species have an important role in inflammatory skin diseases, especially in psoriasis. There are few studies investigating serum oxidant-antioxidant levels in psoriasis. In this study, we aimed to investigate serum oxidant and antioxidant levels in psoriasis and their effects on its pathogenesis. Materials and methods: Included in this study were 50 patients …
Evaluation Of Interleukin-23 Receptor (Il-23r) Gene Polymorphisms And Serum Il-23 Levels In Patients With Psoriasis, Başak Fi̇li̇z, Mehmet Yildirim, Kuyaş Heki̇mler Öztürk, Fevzi̇ye Burcu Şi̇ri̇n, Seda Çeli̇k, İjlal Erturan, Selma Korkmaz, Hi̇kmet Orhan
Evaluation Of Interleukin-23 Receptor (Il-23r) Gene Polymorphisms And Serum Il-23 Levels In Patients With Psoriasis, Başak Fi̇li̇z, Mehmet Yildirim, Kuyaş Heki̇mler Öztürk, Fevzi̇ye Burcu Şi̇ri̇n, Seda Çeli̇k, İjlal Erturan, Selma Korkmaz, Hi̇kmet Orhan
Turkish Journal of Medical Sciences
Background/aim: IL-23R gene polymorphisms and the association of these polymorphisms with serum IL-23 levels were investigated in patients with psoriasis in the current study. Materials and methods: Sixty-seven patients with psoriasis who were admitted to our dermatology outpatient clinic and 67 healthy controls were included in the study. Polymorphisms of the IL-23R gene were determined by KASP-PCR method, and serum IL-23 levels were determined by ELISA method.Results: The distribution of IL-23R gene polymorphisms rs2201841, rs11209026, rs7530511, rs1343152, and rs11465804 was not significantly different in the patient and control groups. The AA genotype of the rs2201841 locus in males and the …
Serum Adropin Levels In Psoriasis Vulgaris And Its Relation With Metabolic Parameters, Selma Korkmaz, Gülben Sayilan Özgün
Serum Adropin Levels In Psoriasis Vulgaris And Its Relation With Metabolic Parameters, Selma Korkmaz, Gülben Sayilan Özgün
Turkish Journal of Medical Sciences
Adropin is a peptide-structure hormone that plays a role in preventing the development of insulin resistance, which has been linked to obesity and metabolic regulation. The purpose of this study is to assess serum adropin levels and their relationship with metabolic parameters in psoriasis vulgaris patients both with and without metabolic syndrome (MetS).Materials and methods: Fifty-three patients and 26 healthy controls were included in this study. Serum adropin levels, fasting blood glucose, fasting serum insulin, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, total cholesterol, and triglyceride levels of all participants were analyzed. Enzyme-linked immunosorbent assay was used to measure serum adropin …