Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 5 of 5
Full-Text Articles in Medicine and Health Sciences
The Role Of Fdg Pet/Ct In Detection Of Distant Metastasis In Theinitial Staging Of Breast Cancer, Anar Aliyev, Sabi̇re Yilmaz Aksoy, Meftune Özhan, Özgül Ekmekçi̇oğlu, Betül Vatankulu, Pinar Çi̇ğdem Kocael, Muhammet Sai̇t Sağer, Meli̇h Engi̇n Erkan, Keri̇m Sönmezoğlu, Meti̇n Halaç
The Role Of Fdg Pet/Ct In Detection Of Distant Metastasis In Theinitial Staging Of Breast Cancer, Anar Aliyev, Sabi̇re Yilmaz Aksoy, Meftune Özhan, Özgül Ekmekçi̇oğlu, Betül Vatankulu, Pinar Çi̇ğdem Kocael, Muhammet Sai̇t Sağer, Meli̇h Engi̇n Erkan, Keri̇m Sönmezoğlu, Meti̇n Halaç
Turkish Journal of Medical Sciences
Background/aim: We aimed to evaluate the role of FDG PET/CT in the detection of extraaxillary regional nodal/distant metastasis in breast cancer patients and to assess the value of FDG PET/CT for detecting distant metastases in patient subgroups. Materials and methods: A total of 254 patients with breast cancer (248 female, 6 male) who underwent PET/CT for initial staging were enrolled. Patients were divided into four groups: Group 1 consisted of 154 patients diagnosed by tru-cut/core/FNAB, Group 2 comprised 32 patients diagnosed by excisional biopsy, Group 3 included 62 patients who had mastectomy-axillary lymph node dissection, and Group 4 consisted of …
Combination Immunotherapy With Extract Of Heated 4t1 And Naloxone In Mouse Model Of Breast Cancer, Shervin Jahangiri, Seyyed Meysam Abtahi Froushani, Norouz Delirezh
Combination Immunotherapy With Extract Of Heated 4t1 And Naloxone In Mouse Model Of Breast Cancer, Shervin Jahangiri, Seyyed Meysam Abtahi Froushani, Norouz Delirezh
Turkish Journal of Medical Sciences
Background/aim: This study was designed to investigate the efficacy of a new vaccine against breast cancer, which was made by mixing the extract of heated 4T1 cells and naloxone, as an adjuvant. Materials and methods: Female BALB/c mice of 6-8 weeks old were challenged subcutaneously in the right flanks with 4T1 cells. When all animals developed a palpable tumor, immunotherapy was initiated. Mice in the experimental groups received, twice with a 1-week interval, either the extract of heated 4T1 alone or in combination with naloxone, and mice in the negative control group received phosphate-buffered saline. One week after the last …
Efficacy Of Pegylated Liposomal Etoposide Nanoparticles On Breast Cancer Cell Lines, Mohammadreza Mehrabi, Parisa Esmaeilpour, Azim Akbarzadeh, Zahra Saffari, Maryam Farahnak, Ali Farhangi, Mohsen Chiani
Efficacy Of Pegylated Liposomal Etoposide Nanoparticles On Breast Cancer Cell Lines, Mohammadreza Mehrabi, Parisa Esmaeilpour, Azim Akbarzadeh, Zahra Saffari, Maryam Farahnak, Ali Farhangi, Mohsen Chiani
Turkish Journal of Medical Sciences
Background/aim: This study aimed to investigate the efficacy of pegylated liposomal etoposide nanoparticles (NPs) against T-47D and MCF-7 breast cancer cell lines. Materials and methods: Pegylated liposomal etoposide NPs were prepared by reverse phase evaporation method. The size, size distribution, and zeta potential of the NPs was measured by a Zetasizer instrument. The cytotoxicity of NPs was inspected by methyl thiazol tetrazolium assay. The release pattern of the drug from the vesicles was studied by the dialysis method. Drug loading and encapsulation efficiency (EE) were also measured. Results: The mean size, size distribution, and zeta potential of pegylated liposomal etoposide …
Examination Of Factors Affecting Women?S Barrier Perception To Participate In Breast Cancer Screenings In A Region Affiliated With A Family Health Center In Turkey, Fatma Ersi̇n, Peri̇han Polat
Examination Of Factors Affecting Women?S Barrier Perception To Participate In Breast Cancer Screenings In A Region Affiliated With A Family Health Center In Turkey, Fatma Ersi̇n, Peri̇han Polat
Turkish Journal of Medical Sciences
Background/aim: This study was conducted in order to determine the factors related to women's barrier perception to participate in breast cancer screenings in a region affiliated with a family health center. Materials and methods: The study was a cross-sectional study. The sample group of the study consisted of 300 women. Descriptive statistics, t test, and Mann-Whitney U test were performed for the analysis of the data. Results: Breast self-examination (BSE) and mammography barrier perception mean score of those who were illiterate in terms of educational status, and BSE and mammography barrier perception mean score of those who were single in …
Quantitative Comparison Of Immunohistochemical And Pcr Analysis Of Midkine Expression In Breast Cancer Types And Serum Midkine Level, Hülya Çeti̇n Sorkun, Meti̇n Akbulut, Yaşar Enli̇, Emre Tepeli̇, Sevgi̇ Özkan, Ergün Erdem
Quantitative Comparison Of Immunohistochemical And Pcr Analysis Of Midkine Expression In Breast Cancer Types And Serum Midkine Level, Hülya Çeti̇n Sorkun, Meti̇n Akbulut, Yaşar Enli̇, Emre Tepeli̇, Sevgi̇ Özkan, Ergün Erdem
Turkish Journal of Medical Sciences
Background/aim: Midkine (MK), a heparin-binding growth factor, has an important role in cancer progression. The aim of this study was to determine MK expression in breast tissue and the preoperative and postoperative serum levels of patients with breast cancer. Materials and methods: Sixty-one patients with breast cancer participated in our study. The MK serum levels were measured pre- and postoperatively for these patients. We also analyzed breast tissues of the 61 patients immunohistochemically. We examined serum midkine levels in 49 healthy volunteers. Results: MK expression was observed in 44 (72.1%) of 61 breast cancer patients. In breast cancer patients the …