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Articles 1 - 30 of 161
Full-Text Articles in Medicine and Health Sciences
P40: The Missing Link Between Autophagy And Cancer?, Mittul Patel
P40: The Missing Link Between Autophagy And Cancer?, Mittul Patel
Kaleidoscope
No abstract provided.
Diurnal Variations Of Genes Contributing To Sodium And Potassium Cardiac Currents, Parvathi Nataraj
Diurnal Variations Of Genes Contributing To Sodium And Potassium Cardiac Currents, Parvathi Nataraj
Kaleidoscope
No abstract provided.
Section Abstracts: Medical Science
Section Abstracts: Medical Science
Virginia Journal of Science
Abstracts of the Medical Science Section for the 89th Annual Meeting of the Virginia Academy of Science, May 25-27, 2011, University of Richmond, Richmond VA.
Epigenetics As An Explanation For Phenotypic Variation In Monozygotic Twins, Marina Pomerantseva
Epigenetics As An Explanation For Phenotypic Variation In Monozygotic Twins, Marina Pomerantseva
The Science Journal of the Lander College of Arts and Sciences
The following is the introduction of this article: Researchers often use twins as natural samples to test hypotheses regarding the contribution of genetic factors to different phenotypes, especially diseases. The classical method is comparing traits in identical, or monozygotic (MZ) twins to those of dizygotic (DZ) twins. This method has had a significant impact on our current understanding of etiologic factors in many diseases which do not follow simple Mendelian law (i.e. complex diseases), including schizophrenia, bipolar disease, and major depression.
President's Message, Justin K. Wyatt
President's Message, Justin K. Wyatt
Journal of the South Carolina Academy of Science
No abstract provided.
Scas Officers And Council Members 2010 - 2011
Scas Officers And Council Members 2010 - 2011
Journal of the South Carolina Academy of Science
No abstract provided.
Properties And Uses Of Sodium Titanates And Peroxotitanates, David Hobbs
Properties And Uses Of Sodium Titanates And Peroxotitanates, David Hobbs
Journal of the South Carolina Academy of Science
No abstract provided.
Scas Officers And Council Members 2010-2011
Scas Officers And Council Members 2010-2011
Journal of the South Carolina Academy of Science
No abstract provided.
Gold Nanospheres As Inhibitors Of Amyloid- Β Protein Aggregation Involved In Alzheimer’S Disease, Mihyun Lim, Deborah Soto-Ortega, Rahina Mahtab, Melissa Moss
Gold Nanospheres As Inhibitors Of Amyloid- Β Protein Aggregation Involved In Alzheimer’S Disease, Mihyun Lim, Deborah Soto-Ortega, Rahina Mahtab, Melissa Moss
Journal of the South Carolina Academy of Science
No abstract provided.
Table Of Contents
Journal of the South Carolina Academy of Science
No abstract provided.
Inverse Correspondence Of Amh And Fsh Levels In Women Presenting For Infertility Treatments, Amara Iverson, Abdelmonium Younis, William Butler, William Roudebush
Inverse Correspondence Of Amh And Fsh Levels In Women Presenting For Infertility Treatments, Amara Iverson, Abdelmonium Younis, William Butler, William Roudebush
Journal of the South Carolina Academy of Science
No abstract provided.
Şerefeddin Sabuncuoğlu’S Drawings Of Gyneco-Obstetric Instruments, Nuri̇ Seli̇m Kadioğlu, Oya Ögenler, İlter Uzel
Şerefeddin Sabuncuoğlu’S Drawings Of Gyneco-Obstetric Instruments, Nuri̇ Seli̇m Kadioğlu, Oya Ögenler, İlter Uzel
Turkish Journal of Medical Sciences
The purpose of our study was to determine the contribution of Şerefeddin Sabuncuoğlu's achievement to bring gynecology to the modern knowledge level. The gynecological tools in the achievement of Serefeddin Sabuncuoğlu, who is the late period representative of classical medical paradigm, are examined in connection with the achievement of Zahravi, which belongs to the classical medical literature. It was determined that in the long time interval from Zahravi to Sabuncuoğlu a limited advancement occurred in medical knowledge, and that the differences between the achievements of the 2 doctors are important for reflecting the development between the 2 periods.
The Second Step In Vitro Trial Of Ankaferd® Bloodstopper®: Comparison With Other Hemostatic Agents, Emre Huri̇, Kadi̇r Turgay Akgül, Mehmet Özgür Yücel, Hesna Müzeyyen Astarci, Hüseyi̇n Üstün, Rüştü Cankon Germi̇yanoğlu
The Second Step In Vitro Trial Of Ankaferd® Bloodstopper®: Comparison With Other Hemostatic Agents, Emre Huri̇, Kadi̇r Turgay Akgül, Mehmet Özgür Yücel, Hesna Müzeyyen Astarci, Hüseyi̇n Üstün, Rüştü Cankon Germi̇yanoğlu
Turkish Journal of Medical Sciences
To investigate the efficacy of Ankaferd Bloodstopper (ABS) and compare ABS with the other hemostatic agents still used in urologic surgery. Materials and methods: Forty Wistar rats were divided into 5 groups: Group T (traditional), partial nephrectomy (PN) with hilar control as per the conventional technique; Group G (Glubran 2), conventional PN followed by the application of Glubran 2; Group F (FloSeal), FloSeal application to the resected area of the kidney; Group C (Celox), Celox was applied; Group A (ABS), Ankaferd was used. Warm ischemia time (WIT) and hemostasis time (HT) were recorded and histopathologic features were compared among the …
In Vitro Efficacy Of Different Chemical Substances On Hydatid Cyst Components, Ömer Faruk Akinci, Mustafa Karaoğlanoğlu, Mustafa Sedat Bozkurt, Leyla Gözaydin, Sali̇h Zeki̇ Zi̇ylan
In Vitro Efficacy Of Different Chemical Substances On Hydatid Cyst Components, Ömer Faruk Akinci, Mustafa Karaoğlanoğlu, Mustafa Sedat Bozkurt, Leyla Gözaydin, Sali̇h Zeki̇ Zi̇ylan
Turkish Journal of Medical Sciences
Cyst membrane, daughter cyst, and pericyst are the focal point of some problems related to the percutaneous treatment of hydatid disease. This study was planned to investigate the in vitro efficacy of sodium hypochlorite, hydrogen peroxide, some widely used scolicidal agents, and some chemical solvents on hydatid cyst components. Materials and methods: To investigate the effects of various pharmacological and chemical agents on hydatid cyst components, 5 mL each of 15 different agents was put into bottles. Tissue measuring 2 × 1 cm was cut from the pericyst and the cyst membrane was put into each bottle. Two undamaged daughter …
Hypolipidemic And Antioxidant Activity Of Aqueous Extract Of Monascus Purpureus Fermented Indian Rice In High Cholesterol Diet Fed Rats, Aiyalu Rajasekaran, Muthusamy Kalaivani
Hypolipidemic And Antioxidant Activity Of Aqueous Extract Of Monascus Purpureus Fermented Indian Rice In High Cholesterol Diet Fed Rats, Aiyalu Rajasekaran, Muthusamy Kalaivani
Turkish Journal of Medical Sciences
To evaluate hypolipidemic and anti-oxidant activities of Monascus purpureus fermented Indian variety of rice. Materials and methods: Indian rice variety IR-532-E-576 was fermented with Monascus purpureus MTCC 1090 (Monascaceae) and extracted with water by boiling. Experimentally induced hyperlipidemia was produced by feeding rats with 2% cholesterol enriched diet for 15 days. Afterwards hypercholesterolemic rats were orally administered with Monascus fermented Indian rice extract at the dose of 1.2 and 2.4 mg/kg bw along with high cholesterol diet for 30 successive days in order to evaluate their expected hypolipidemic activity. Plasma lipid parameters such as total cholesterol, triglycerides, LDL (low density …
The Optimal Dose Of Vitamin D In Growing Girls During Academic Years: A Randomized Trial, Mehrdad Shakinba, Samane Tefagh, Zahra Nafei
The Optimal Dose Of Vitamin D In Growing Girls During Academic Years: A Randomized Trial, Mehrdad Shakinba, Samane Tefagh, Zahra Nafei
Turkish Journal of Medical Sciences
Prevalence of vitamin D deficiency is remarkable during childhood and adolescence throughout the world. Sufficient intake of vitamin D contributes to a number of health outcomes. The aim of this study was to specify the optimal dose of vitamin D in growing girls in a Muslim country during an academic year. Materials and methods: This randomized clinical trial study was carried out in Yazd in the center of Iran in 2007;120 junior high school girls (aged 12-15 years) were randomly divided into 4 groups. Sixty students in groups I and II were treated for vitamin D deficiency with 300,000 IU …
Single Or Double Sperm Wash Processing By Density Gradient Centrifugation: Effect On Clomiphene Citrate Induced Intrauterine Insemination Cycle Outcomes, Ni̇lgün Turhan, Aslihan Pekel, Yüksel Onaran, Zehra Candan İltemi̇r Duvan, Ömer Bayrak
Single Or Double Sperm Wash Processing By Density Gradient Centrifugation: Effect On Clomiphene Citrate Induced Intrauterine Insemination Cycle Outcomes, Ni̇lgün Turhan, Aslihan Pekel, Yüksel Onaran, Zehra Candan İltemi̇r Duvan, Ömer Bayrak
Turkish Journal of Medical Sciences
To compare the motility yields of single or double wash after density gradient centrifugation of the ejaculate and their effects on pregnancy rates in clomiphene citrate induced intrauterine insemination (IUI) cycles. Materials and methods: This prospective randomized controlled study included 341 IUI cycles. Sperm specimens processed by density gradient centrifugation either with single wash (the single wash group, n = 170) or double wash treatment (the double wash group, n = 171). Sperm parameters before and after the preparation and the cycle outcomes were evaluated. The main outcome measure was the pregnancy rate. Results: The prewash sperm concentrations, the total …
Plasma Adiponectin And Resistin Levels In Women With Polycystic Ovary Syndrome: Relation To Body Mass Index And Insulin Resistance, Emre Di̇kmen, İlhan Tarkun, Funda Öztürk, Berri̇n Arslan, Zeynep Cantürk
Plasma Adiponectin And Resistin Levels In Women With Polycystic Ovary Syndrome: Relation To Body Mass Index And Insulin Resistance, Emre Di̇kmen, İlhan Tarkun, Funda Öztürk, Berri̇n Arslan, Zeynep Cantürk
Turkish Journal of Medical Sciences
To compare the serum levels of adiponectin and resistin between patients with polycystic ovary syndrome (PCOS) and healthy control subjects matched for age and body mass index (BMI), and to assess possible correlations of adiponectin and resistin to the hormonal and metabolic parameters of the syndrome. Materials and methods: Fifty five patients with PCOS diagnosis composed of 25 obese, 13 overweight, 17 normal weight subjects, and 49 healthy women matched for age and BMI were included in this study. Hormone and lipid profile, adiponectin, and resistin were measured in all cases. Results: Serum adiponectin levels were similar in the lean …
Effects Of 50 Hz Electric Field On Malondyaldehide And Nitric Oxide Levels In Spinal Cord Of Rats At Prenatal Plus Postnatal Period, Ertuğrul Uzar, Haci Ramazan Yilmaz, Mustafa Yilmaz, Efkan Uz, Vedat Ali̇ Yürekli̇, Bumi̇n Dündar, Hasan Rifat Koyuncuoglu, Selçuk Çömlekçi̇
Effects Of 50 Hz Electric Field On Malondyaldehide And Nitric Oxide Levels In Spinal Cord Of Rats At Prenatal Plus Postnatal Period, Ertuğrul Uzar, Haci Ramazan Yilmaz, Mustafa Yilmaz, Efkan Uz, Vedat Ali̇ Yürekli̇, Bumi̇n Dündar, Hasan Rifat Koyuncuoglu, Selçuk Çömlekçi̇
Turkish Journal of Medical Sciences
The effect of 50 Hz electric field (EF) on developing neural tissues is not known. We aimed to determine whether there would be any oxidative stress effect of 50 Hz EF on developing spinal cord tissues of pup rats by evaluating malondialdehyde (MDA), nitric oxide (NO) levels, and antioxidant enzyme activities such as superoxide dismutase (SOD) and catalase (CAT) measurement. Materials and methods: In the prenatal+postnatal group, the pregnant rat was exposed to continuous EF at 50 Hz 10 kV/s until delivery. Then the female pups of this group (n = 7) were exposed to EF at the same doses …
Immunohistochemical Evaluation Of The Effects Of Nebivolol On Intimal Hyperplasia Following Endothelial Injury, İlker Akar, Ali̇ Rahman, M. Cengi̇z Çolak, Bi̇lal Üstündağ, İbrahi̇m Hani̇fi̇ Özercan, Ayhan Uysal
Immunohistochemical Evaluation Of The Effects Of Nebivolol On Intimal Hyperplasia Following Endothelial Injury, İlker Akar, Ali̇ Rahman, M. Cengi̇z Çolak, Bi̇lal Üstündağ, İbrahi̇m Hani̇fi̇ Özercan, Ayhan Uysal
Turkish Journal of Medical Sciences
Intimal hyperplasia is a vascular remodeling process. It is a clinical problem that forms in the vascular wall as a result of smooth muscle cell migration, proliferation, and extracellular matrix accumulation. In this study we examined the immunohistochemical evaluation of the effects of nebivolol on intimal hyperplasia in damaged endothelial tissue. Materials and methods: The study was conducted using 21 rabbits equally divided into 3 groups: control, solvent, and nebivolol. The rabbits in the control group only underwent balloon injury of the abdominal aorta. The rabbits in the solvent group and nebivolol group underwent balloon injury and were treated with …
Efficacy Of Hyaluronic Acid - Carboxymethyl Cellulose Membrane (Seprafilm®) And Polylactic Acid Barrier Film (Surgiwrap™) For The Prevention Of Adhesions After Thyroid Surgery: An Experimental Model, Gökhan Çi̇pe, Hakan Mustafa Köksal, Sadik Yildirim, Mustafa Fevzi̇ Celayi̇r, Adi̇l Baykan
Efficacy Of Hyaluronic Acid - Carboxymethyl Cellulose Membrane (Seprafilm®) And Polylactic Acid Barrier Film (Surgiwrap™) For The Prevention Of Adhesions After Thyroid Surgery: An Experimental Model, Gökhan Çi̇pe, Hakan Mustafa Köksal, Sadik Yildirim, Mustafa Fevzi̇ Celayi̇r, Adi̇l Baykan
Turkish Journal of Medical Sciences
Adhesions occurring after initial surgery increase complications in secondary thyroid operations. Therefore use of anti-adhesive barriers may reduce complication rates of secondary thyroid operations. In this study, we investigated the efficacy of hyaluronic acid-carboxymethyl cellulose membrane (HA-CMC, Seprafilm®) and polylactic acid barrier film (PLA, Surgiwrap™) in reducing adhesions after thyroid surgery. Materials and methods: A randomized-controlled experimental animal model was utilized. Forty-eight male Wistar Albino rats were randomly divided into 3 equal groups, forming study and control groups. Thyroid surgery was performed in all subjects. HA-CMC and PLA were applied between the thyroid zone and strap muscles after thyroid surgery …
Comparison Of Growth Factor Levels In Patients With Normal And Hypospadiac Prepuce*, Tutku Soyer, Ebru Şebnem Ayva, Pinar Atasoy, Mustafa Kemal Aslan, Ahmet Murat Çakmak
Comparison Of Growth Factor Levels In Patients With Normal And Hypospadiac Prepuce*, Tutku Soyer, Ebru Şebnem Ayva, Pinar Atasoy, Mustafa Kemal Aslan, Ahmet Murat Çakmak
Turkish Journal of Medical Sciences
To compare the growth factor levels in patients with normal and hypospadiac prepuce. Materials and methods: Patients who underwent hypospadias repair were included in the study. The prepuce was excised after achieving successful hypospadias repair with satisfactory functional and cosmetic appearance. The patients who underwent preputial reconstructions and complicated repairs were excluded. The control group consists of boys without hypospadias. Elective circumcision was performed to have normal preputial samples. The VEGF levels, VEGF receptor (VEGFR) and TGF-\beta receptor (TGF-\beta-R) expressions were evaluated in preputial tissues by immunohistochemical analysis. Results: Fifteen patients were included in each group. The mean age of …
Atypical Acute Urticaria In Children And Its Relationship With Urticarial Vasculitis, Zafer Arslan, Serap Özmen, Sara Sürmeli̇, Ni̇lüfer Arda
Atypical Acute Urticaria In Children And Its Relationship With Urticarial Vasculitis, Zafer Arslan, Serap Özmen, Sara Sürmeli̇, Ni̇lüfer Arda
Turkish Journal of Medical Sciences
In childhood, urticarial lesions are sometimes associated with purpura. This form might be identified as atypical, and may also be related to urticarial vasculitis (UV). The aim of this study was to assess the clinicopathologic characteristics of UV in children with atypical urticaria. Materials and methods: Fifteen children with atypical urticaria were evaluated with medical history, physical examination, and laboratory and skin punch biopsy findings. Results: Infections were detected as possible precipitating factor in 12 patients. Complement levels were normal in all. On histological examination, 6 patients (40%) had neutrophil-predominant infiltrate and 9 (60%) patients had lymphocyte-predominant infiltrate. All the …
Adverse Events Associated With Exchange Transfusion And Etiology Of Severe Hyperbilirubinemia In Near-Term And Term Newborns, Ali̇ Bülbül, Feri̇de Füsun Okan, Emel Kabakoğlu Ünsür, Asi̇ye Nuhoğlu
Adverse Events Associated With Exchange Transfusion And Etiology Of Severe Hyperbilirubinemia In Near-Term And Term Newborns, Ali̇ Bülbül, Feri̇de Füsun Okan, Emel Kabakoğlu Ünsür, Asi̇ye Nuhoğlu
Turkish Journal of Medical Sciences
To assess clinical features, etiology, and complications in term and near-term newborns who received exchange transfusion. Materials and methods: Infants with >=35 gestational weeks admitted to our neonatal intensive care unit in the first 30 days of life and underwent exchange transfusion due to severe hyperbilirubinemia between 2002 and 2008 were included. Clinical features, etiology of hyperbilirubinemia, and complications of exchange transfusion were assessed. Results: Exchange transfusion was performed 86 times in a total of 73 patients. Eleven patients received exchange transfusion twice, and 1 patient 3 times. A great proportion of the patients (61.6%) were male, and mean (± …
Urginea Maritima (L.) Baker (Liliaceae) Extract Induces More Cytotoxicity Than Standard Chemotherapeutics In The A549 Non-Small Cell Lung Cancer (Nsclc) Cell Line, Hakan Bozcuk, Mustafa Özdoğan, Oktay Aykurt, Fati̇h Topçuoğlu, Hasan Öztürk, Deni̇z Eki̇nci̇, Asuman Karadeni̇z, Ayli̇n Mutlu, Durmuş Burgucu
Urginea Maritima (L.) Baker (Liliaceae) Extract Induces More Cytotoxicity Than Standard Chemotherapeutics In The A549 Non-Small Cell Lung Cancer (Nsclc) Cell Line, Hakan Bozcuk, Mustafa Özdoğan, Oktay Aykurt, Fati̇h Topçuoğlu, Hasan Öztürk, Deni̇z Eki̇nci̇, Asuman Karadeni̇z, Ayli̇n Mutlu, Durmuş Burgucu
Turkish Journal of Medical Sciences
Urginea maritima (Um) is a plant native to especially Turkey and the Mediterranean area. In this study, we investigated whether Um extract exerted cytotoxicity on cancer cells. Materials and methods: We made various extracts of Um. These extracts in varying concentrations were added to an A549 NSCLC cell culture, alone or with gemcitabine and/or cisplatin. Growth inhibition was tested by the MTT assay and an Annexin V-FITC apoptosis detection kit Results: The onion Um extract (1 µg/mL) was more cytotoxic than cisplatin (1 µg/mL), gemcitabine (1 nm/mL), and leaf Um extract (1 µg/mL) with P < 0.001, P = 0.097, and P < 0.001, respectively. The efficacy of Um extract was further improved by the addition of an antioxidant cocktail to an IC_{50} value of 0.02 µg/mL. Conclusion: Um extract has been shown for the first time to be a strong candidate for drug development in solid tumors. Our studies continue to further define the specific antitumor compound(s) in this extract.
Ex Vivo Produced Oral Mucosa Equivalent Preliminary Report: A Technical Note, Gürkan Raşi̇t Bayar
Ex Vivo Produced Oral Mucosa Equivalent Preliminary Report: A Technical Note, Gürkan Raşi̇t Bayar
Turkish Journal of Medical Sciences
The aim of this study was to produce of ex vivo oral mucosal equivalent. The continuous stratified layer of human oral keratinocytes was grown on a cadaveric human dermal matrix in a defined culture medium without a feeder layer. Materials and methods: Human oral keratinocytes from a keratinized oral mucosa biopsy specimen were enzymatically dissociated and cultured in a serum-free defined culture medium, "EpiLife" (Cascade Biologics, Portland, OR, USA), containing a low calcium concentration of 0.06 mM. Oral keratinocytes were expanded one passage. Once a sufficient population of keratinocytes was reached, they were seeded onto the type IV collagen coated …
Evaluation Of Gdx Parameters By Using Information Theory, Umut Arslan, Banu Bozkurt, Ahmet Ergun Karaağaoğlu, Murat Tanju İrkeç
Evaluation Of Gdx Parameters By Using Information Theory, Umut Arslan, Banu Bozkurt, Ahmet Ergun Karaağaoğlu, Murat Tanju İrkeç
Turkish Journal of Medical Sciences
To evaluate the performance of GDx parameters in the diagnosis of glaucoma by using information theory and compare the results obtained using receiver operating characteristic (ROC) curve analysis, which is a traditional method. Materials and methods: Retinal nerve fiber layer thickness was measured in 270 eyes with glaucoma and 81 normal eyes with scanning laser polarimeter (NFA GDx version, 1.0.08), and 14 GDx parameters were calculated. Both ROC curve analysis and information theory were used to determine the best GDx parameters. The best cut-off points of these parameters were obtained using information theory for glaucoma prevalence (Pr) of 1%, 2%, …
Which Predicts The Cardiovascular Risk Best In Elderly Metabolic Syndrome Patients: Atp Iii Or Idf?, Serpi̇l Aydin, Ayfer Gemalmaz, Tufan Nayi̇r, Şule Özkan
Which Predicts The Cardiovascular Risk Best In Elderly Metabolic Syndrome Patients: Atp Iii Or Idf?, Serpi̇l Aydin, Ayfer Gemalmaz, Tufan Nayi̇r, Şule Özkan
Turkish Journal of Medical Sciences
As metabolic syndrome (MetS) is one of the major determinants of cardiovascular disease, it is important to detect and intervene with MetS in order to minimize cardiovascular risk. The objectives of this study were to identify the prevalence of MetS in our elderly patients and to evaluate the ability IDF and ATP III to predict the cardiovascular risk. Materials and methods: This cross-sectional study included patients above 65 years attending the outpatient clinic of a hospital over a 4-year period and who gave oral informed consent for participation in the study. ATP III and IDF criteria were compared according to …
Evaluation Of The Tick Bites In A Crimean-Congo Haemorrhagic Fever (Cchf) Endemic Area In Turkey, Serpi̇l Erol, Ahmet Yeni̇solak, Göknur Yapar Toros, Ayşe Albayrak
Evaluation Of The Tick Bites In A Crimean-Congo Haemorrhagic Fever (Cchf) Endemic Area In Turkey, Serpi̇l Erol, Ahmet Yeni̇solak, Göknur Yapar Toros, Ayşe Albayrak
Turkish Journal of Medical Sciences
After the first description of a CCHF outbreak in Turkey, tick bites became an increasing cause of visits to health-care facilities. In this study, we evaluated tick bites in a CCHF endemic region. Materials and methods: The study included cases of tick bites that were referred to 2 hospitals in Erzurum between June and October 2008. All cases were followed-up for 10 days for the results of CCHF. Results: During the study period, 161 patients were admitted for a tick bite. The majority (56.3%) were farmers and housewives. Children ≤ 13 years of age were bitten mostly on the head …
Invasive Device-Associated Nosocomial Infections Of A Teaching Hospital In Turkey; Four Years’ Experience, Aslihan Candevi̇r, Behi̇ce Kurtaran, Fi̇li̇z Ki̇bar, Emre Karakoç, Hasan Sali̇h Zeki̇ Aksu, Yeşi̇m Taşova
Invasive Device-Associated Nosocomial Infections Of A Teaching Hospital In Turkey; Four Years’ Experience, Aslihan Candevi̇r, Behi̇ce Kurtaran, Fi̇li̇z Ki̇bar, Emre Karakoç, Hasan Sali̇h Zeki̇ Aksu, Yeşi̇m Taşova
Turkish Journal of Medical Sciences
To determine our setting's IDAI rates, infecting microorganisms, and their resistance patterns to achieve standardization and make comparisons among other Turkish and developed country hospitals all over the world. Materials and methods: The numbers of total patient days, ventilator days, central catheter days and, urinary catheter days in the ICUs were recorded and IDAI rates were calculated. Clinical specimens were obtained from patients, cultivated at appropriate culture media, and infecting microorganisms and resistance patterns were determined. Results: Totally 1450 invasive device-associated infection episodes were determined (16.4% of patients) with a rate of 21.12/1000 days. Ventilator associated pneumonia rate was 22.05/1000 …