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Effects Of Crocin On Experimental Obesity And Type-2 Diabetes, Ömer Hazman, Laçi̇ne Aksoy, Ahmet Büyükben
Effects Of Crocin On Experimental Obesity And Type-2 Diabetes, Ömer Hazman, Laçi̇ne Aksoy, Ahmet Büyükben
Turkish Journal of Medical Sciences
Background/aim: The aim of this study is to scrutinize the effects of crocin on obesity and type-2 diabetes, with an approach that takes oxidative stress and inflammatory parameters into account. Materials and methods: The experimental obesity model was created by utilizing a 10-week-long high-fat diet (HFD). An experimental type-2 diabetes model was created by injecting multiple low-dose streptozocin (STZ) injections into rats that were fed with the HFD. The treatment groups were administered a daily crocin dose of 150 mg/kg for 6 weeks via gavage. Results: Findings of the study demonstrated that crocin could be effective in relieving the symptoms …