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Articles 1 - 8 of 8
Full-Text Articles in Medicine and Health Sciences
Beyond Mitragynine: Composition Survey And Stability Assessment Of Kratom Tea Ordered Via Food Delivery Platforms In Bangkok, Thailand, Yuta Tokuda, Apinya Tubtimrattana, Nat Tansrisawad, Kornvalee Meesilpavikkai, Parath Thirati
Beyond Mitragynine: Composition Survey And Stability Assessment Of Kratom Tea Ordered Via Food Delivery Platforms In Bangkok, Thailand, Yuta Tokuda, Apinya Tubtimrattana, Nat Tansrisawad, Kornvalee Meesilpavikkai, Parath Thirati
Chulalongkorn Medical Journal
Background: Kratom is a native tree to Southeast Asia. Kratom leaves have long been used medicinally and recreationally due to their stimulative and opioid-like effects attributed to high endogenous levels of mitragynine and related alkaloids. Kratom is widely consumed as tea and is now publicly sold, including on food delivery platforms, after recent decriminalization despite selling of kratom products being still considered illegal by other acts.
Objectives: To assess the formulas of kratom teas sold on Thai food delivery platform together with their consistency and the stability of refrigerated teas.
Methods: Kratom alkaloids, mitragynine and 7-hydroxymitragynine, and additive contents of …
The Symptoms And Management Of Children With Attention-Deficit/Hyperactivity Disorder During Covid-19 Pandemic At The Child And Adolescent Psychiatry Clinic, King Chulalongkorn Memorial Hospital, Nuttorn Pityaratstian
The Symptoms And Management Of Children With Attention-Deficit/Hyperactivity Disorder During Covid-19 Pandemic At The Child And Adolescent Psychiatry Clinic, King Chulalongkorn Memorial Hospital, Nuttorn Pityaratstian
Chulalongkorn Medical Journal
Background: The coronavirus disease 2019 (COVID-19) pandemic has caused abrupt changes in almost everybody’s life, particularly children. Children and adolescents with attention-deficit hyperactivity disorder (ADHD) have difficulties in many aspects in lives and may have worsening of the symptoms during the pandemic.
Objectives: This cross-sectional descriptive study aimed to investigate the changes of the ADHD symptoms and managements of children with ADHD during the first lockdown and after-lockdown period.
Methods: Parent-reported questionnaires i.e. the Swanson, Nolan, and Pelham Rating Scale-IV (SNAP-IV) and a demographic questionnaire, were applied to collect data from 109 children with ADHD aged between 4 -18 years …
Detection Of Pathogenic Leptospira Spp. By Rpa-Nalfia Targeting Lipl32 Gene, Nattachai Srisawat
Detection Of Pathogenic Leptospira Spp. By Rpa-Nalfia Targeting Lipl32 Gene, Nattachai Srisawat
Chulalongkorn Medical Journal
Background: Lack of available sensitive point-of-care tests is one of the key challenges limiting the early point-of-care diagnosis of leptospirosis.Previously, a Recombinase Polymerase Amplification (RPA) and clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated protein 12a (CRISPR/Cas12a) lipL32 detection platform with high sensitivity and specificity was developed. However, its turnaround time is between one and two hours, and two reactions are required.
Objective: To develop the RPA in combination with a nucleic acid lateral flow immunoassay (NALFIA) detection platform to reduce the turnaround time and make it a one-step reaction.
Methods: RPA combined with nucleic acid lateral flow immunoassay (NALFIA) detection …
Effects Of Fine Particulate Matter On Hospital Admission Due To Stroke In A Business City Of Thailand, Piyanee Kasiravat
Effects Of Fine Particulate Matter On Hospital Admission Due To Stroke In A Business City Of Thailand, Piyanee Kasiravat
Chulalongkorn Medical Journal
Background: About 99.0% of global population was living in the area where air pollutant levels exceed World Health Organization Standard. Particulate matter whose diameter is equal to or less than 2.5 microns (PM2.5), is an important risk factor for chronic diseases including chronic respiratory diseases, heart diseases and lung cancer. However, the association between PM2.5 and cerebrovascular event is still controversial, especially in Asian populations.
Objective: To assess the association between PM2.5 and hospital admissions due to stroke.
Methods: A retrospective study was conducted using air monitoring and health data during 2017 - 2019 in Hatyai, a business city in …
Mandibular Plane To Hyoid In Lateral Cephalometry As A Predictive Parameter For Severity Of Obstructive Sleep Apnea, Likhit Khattiyawittayakun
Mandibular Plane To Hyoid In Lateral Cephalometry As A Predictive Parameter For Severity Of Obstructive Sleep Apnea, Likhit Khattiyawittayakun
Chulalongkorn Medical Journal
Background: Obstructive sleep apnea (OSA) is a common disorder affecting at least 2.0% to 4.0% of the adult population. Early diagnosis and treatment can reduce patient burden. A lateral cephalometric radiograph (LCR) is one method to evaluate upper airway obstruction in patients with OSA.
Objective: This crosssectional study was aimed to investigate the predictive performance of mandibular plane to hyoid (MPH) in LCR for determining the OSA severity.
Methods: One hundred and three adult subjects were analyzed. LCR was performed under standardized processes and measured twice on separate occasions. Receiver operating characteristic (ROC) curve analysis was performed to obtain the …
Depression, Smartphone Addiction And Association Factors Among Preclinical Medical Students, Aticha Wattanaudomchai
Depression, Smartphone Addiction And Association Factors Among Preclinical Medical Students, Aticha Wattanaudomchai
Chulalongkorn Medical Journal
Background: There were few studies of smartphone addiction behavior has been found in preclinical medical students.
Objective: To determine the prevalence and associated factors of depression of smartphone addiction behavior among preclinical medical students of Chulalongkorn University.
Methods: This is a cross-sectional descriptive study. The data were collected from preclinical medical students at Chulalongkorn University in 2020 academic year, prior to COVID-19 pandemic in Thailand. The instruments included the Smartphone Addiction Scale Thai version (SAS-SV-TH), Patient Health Questionnaire-9 Thai version (PHQ-9-T), Pittsburgh Sleep Quality Index Thai version (PSQI-T), and Thai Interpersonal questionnaire. The data were analyzed using SPSS version 25. …
Urinary Oxalate Excretion Is Increased In Calcium Oxalate Nephrolithiasis Patients And Associated With Increased Urinary Capacity Of Calcium Oxalate Crystallization, Chanchai Boonla
Chulalongkorn Medical Journal
Background: Calcium oxalate (CaOx) stone is the most common type of stones formed in the urinary tract. Formation of CaOx stone is driven by increased CaOx crystallization in urine.
Objective: To develop a new test, called indole-reacted calcium oxalate crystallization index (iCOCI), and to measure the capability of urine to produce CaOx crystals.
Methods: One hundred samples of 24-h human urine samples obtained from CaOx stone-forming subjects (SFS, n = 50) and non-stone subjects (NSS, n = 50). The levels of oxalate were determined by two methods, i.e., oxalate oxidase method and iCOCI test. Unpaired student t - test, Pearson’s …
Evaluation Of Aspartate Aminotransferase To Platelet Ratio Index And Fibrosis 4 Score For Selecting Patients With Chronic Hepatitis B To Perform Liver Fibrosis Assessment By Transient Elastography In Resource-Limited Areas, Puth Muangpaisarn
Chulalongkorn Medical Journal
Background: Liver stiffness measurement operated by transient elastography (TE) becomes a noninvasive method to assess the severity of hepatic fibrosis. However, TE may not be available in resource-limiting areas. Therefore, simple serum biomarker scoring should be evaluated for fibrotic assessment instead of TE.
Objectives: This study aimed to evaluate the diagnostic performance of aspartate. aminotransferase to platelet ratio index (APRI) and fibrosis-4 (FIB-4) scores compared with TE in chronic hepatitis B (CHB) patients and determine the optimal cut-off values to select the CHB patients who should be referred to higher-level hospital for TE evaluation.
Methods: We conducted a cross-sectional study …