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Articles 1 - 5 of 5
Full-Text Articles in Medicine and Health Sciences
Proposed Method For Measuring The Let Of Radiotherapeutic Particle Beams, Stephen D. Bello
Proposed Method For Measuring The Let Of Radiotherapeutic Particle Beams, Stephen D. Bello
Physics & Astronomy ETDs
The Bragg peak geometry of the depth dose distributions for hadrons allows for precise and effective dose delivery to tumors while sparing neighboring healthy tissue. Further, compared against other forms of radiotherapeutic treatments, such as electron beam therapy (EBT) or photons (x and \(\gamma\)-rays), hadrons create denser ionization events along the particle track, which induces irreparable damage to DNA, and thus are more effective at inactivating cancerous cells. The measurement of radiation's ability to inactivate cellular reproduction is the relative biological effectiveness (RBE). A quality related to the RBE that is a measurable physical property is the linear energy transfer …
Web Resources For Physician Wellness, Elizabeth C. Lawrence
Web Resources For Physician Wellness, Elizabeth C. Lawrence
Office of Physician and Student Wellness (OPSW)
A current listing of websites, TED talks, and podcasts related to physician wellness and resiliency.
Bibliography Of Physician Wellness Resources, Elizabeth C. Lawrence
Bibliography Of Physician Wellness Resources, Elizabeth C. Lawrence
Office of Physician and Student Wellness (OPSW)
Current list of articles and books on physician wellness.
Unm Gme Resources - July 2017, Elizabeth C. Lawrence
Unm Gme Resources - July 2017, Elizabeth C. Lawrence
Office of Physician and Student Wellness (OPSW)
No abstract provided.
Validation Of The Pre-B Cell Receptor As A Therapeutic Target In B Cell Precursor Acute Lymphoblastic Leukemia, Michael F. Erasmus
Validation Of The Pre-B Cell Receptor As A Therapeutic Target In B Cell Precursor Acute Lymphoblastic Leukemia, Michael F. Erasmus
Biomedical Sciences ETDs
This dissertation is built upon the fundamental idea that the pre-B cell receptor (pre-BCR) is important to leukemia cell survival and a logical therapeutic target in B cell precursor acute lymphoblastic leukemia (BCP-ALL). The pre-BCR is expressed early at a specific stage during B cell development where it plays a central role in survival of healthy B lymphocytes. This receptor is composed of the membrane heavy chain (mIgμ) associated with surrogate light chain components, 5 and VpreB. Through the use of advanced imaging modalities, in particular two-color single particle tracking (SPT), we showed that pre-BCRs formed transient, homotypic interactions. These …