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Articles 1 - 10 of 10
Full-Text Articles in Medicine and Health Sciences
The Use Of Embark In Teaching About Genetic Relatedness, Anna Bonvillain, Tori Trammel
The Use Of Embark In Teaching About Genetic Relatedness, Anna Bonvillain, Tori Trammel
Honors Theses
Because of the increasing importance of precision medicine, it is vital that future healthcare providers master concepts related to genetic variation taught during their undergraduate classes. However, studies have shown that physicians often lack an adequate understanding of genetics, which serves as a hindrance to effectively caring for their patients. To address this issue, we created a collaborative active-learning protocol to improve pre-health students' comprehension of key concepts such as genetic relatedness and the source of genetic variation between siblings. Our worksheet guides students to compare the genetic profiles of two canine siblings using the Embark DNA genotyping platform. Embark …
Rates And Perceptions Of Covid-19 Vaccination From University Of Mississippi Students, Josie Parham
Rates And Perceptions Of Covid-19 Vaccination From University Of Mississippi Students, Josie Parham
Honors Theses
The trials, tribulations and triumphs of the global COVID-19 pandemic are impacted by and are a product of behaviors that occur at the level of nations, states, cities and, ultimately, communities. In the wake of the development of safe and effective vaccines against SARS-CoV2, the virus responsible for the pandemic, the significance of the vaccine is closely linked to the number of individuals that receive the vaccine. To date, surveys have measured sizable variations in vaccination rates between nations, states, cities, and communities. Focusing on events that have transpired in one such local community, the present study (i) measured the …
The Effects Of Astrocytic Derived Insulin-Like Growth Factor (Igf-1) On Cognition And Astrocytes, Destiny Wilson
The Effects Of Astrocytic Derived Insulin-Like Growth Factor (Igf-1) On Cognition And Astrocytes, Destiny Wilson
Honors Theses
Insulin-like growth factor 1 (IGF-1) is a neuroendocrine signaling hormone that plays a vital role in growth and development, as well as learning and memory. Inhibition of this hormone results in cognitive impairments like those seen with age-related decline. While a majority of research has focused on the role of IGF-1 on neurons, the role of astrocytes still needs to be explored. Our research investigates how astrocytes and cognition are affected as a result of direct regulation of localized IGF-1 production in early development and after puberty. Preliminary studies in our laboratory established a connection between IGF-1 and glial fibrillary …
The Effects Of Thc On Hiv Tat Protein-Mediated Neuroinflammation, Camille Martin
The Effects Of Thc On Hiv Tat Protein-Mediated Neuroinflammation, Camille Martin
Honors Theses
Although antiretroviral therapies have allowed people living with human immunodeficiency virus (HIV) to achieve normal life expectancies, they cannot cure HIV nor the neurological symptoms associated with infection, termed neuroHIV. NeuroHIV describes a myriad of neurological disorders including mood disorders (depression and anxiety), cognitive impairment, neuropathic pain, and motor disinhibition. The mechanisms by which HIV promotes neurological impairment are not known, but may involve actions of its neurotoxic proteins. One such protein that has been well-characterized is the HIV trans-activator of transcription (Tat). Tat exerts neurotoxic effects via various means, one of which is to activate microglia, the macrophages of …
Assessment Of Spatial Skills In Human Anatomy And Physiology Students, Abigail Carroll
Assessment Of Spatial Skills In Human Anatomy And Physiology Students, Abigail Carroll
Honors Theses
Visual spatial skills are an individual’s ability to mentally and manipulate the shapes, forms and positions of objects. Spatial skills are necessary for adequate learning in many settings. Few studies have assessed spatial skills compared to success in Anatomy and Physiology in undergraduate students. Most students in this course are on a health profession track. Due to the increasing health care demands and need for competent health care professionals, this study assesses the innate spatial skill ability in students and acquired additional learned spatial skills. This study tests 17 students with the paper-folding test, blank page test, and two surveys …
Finding The Optimal Ionic Liquid To Target White Blood Cell Subpopulations Using Nanoparticles, Meghan Gorniak
Finding The Optimal Ionic Liquid To Target White Blood Cell Subpopulations Using Nanoparticles, Meghan Gorniak
Honors Theses
Disorders and diseases of the immune system have become more prevalent in recent decades and can have life-threatening effects on those afflicted. Granulocyte disorders disproportionately affect infants and children, while chronic lymphocytic leukemia is the most common type of leukemia in adults. Unfortunately, current treatments have many drawbacks such as everyday injection, short-lived efficacy, and unknown levels of safety and effectiveness. It is imperative to find more effective treatment options that could allow for easier drug delivery to specific populations of white blood cells (WBCs). Nanoscale medicine shows promising application, but complications remain in reaching the desired target site and …
The Neuroprotective Effects Of Estradiol And Genistein In Zebra Finch Cerebellum, Renee E. Breaux
The Neuroprotective Effects Of Estradiol And Genistein In Zebra Finch Cerebellum, Renee E. Breaux
Honors Theses
The estradiol (E2) synthetic pathway converts testosterone to E2 via aromatase (AROM) and plays an important role in neuroplasticity. However, exogenous E2 increases cancer risk and interferes with gonadal function. Phytoestrogens, plant-based estrogens, may provide neuroprotection without negative E2 effects. Genistein (GEN), a soy phytoestrogen, preferentially binds to estrogen receptor beta (ER β), which is expressed at a relatively higher concentration than ER α in the cerebellum (CB). The songbird CB is an ideal model for steroid-mediated plasticity. Songbird brains are highly plastic and CB contains all steroid-synthetic enzymes. Previous studies in zebra finches (ZF) have shown that AROM and …
Characterizing The Roles Of Cannabinoid Receptor 1 & 2 In Zebrafish Behavior, Metabolism, And Seizure-Induced Activity, Kayci Kimmons
Characterizing The Roles Of Cannabinoid Receptor 1 & 2 In Zebrafish Behavior, Metabolism, And Seizure-Induced Activity, Kayci Kimmons
Honors Theses
Epileptic disorders like Dravet Syndrome require novel studies to determine the most ideal treatment. New research linking the endocannabinoid system (ECS) to epileptic disorders is arising, but there is still much to be discovered about the function and regulatory impact of the endocannabinoid system and its receptors in epilepsies like Dravet. In this study, knockout models of larval and adult zebrafish (Danio rerio) were used to investigate the roles of cannabinoid receptors 1 & 2 in behavior, brain mitochondrial metabolism, and seizure-induced activity following exposure to THC and CBD. Larval zebrafish which lacked cannabinoid receptor 1 exhibited increased …
Analysis Of Test Anxiety In Human Anatomy And Physiology I Students At The University Of Mississippi, Anne Piazza
Analysis Of Test Anxiety In Human Anatomy And Physiology I Students At The University Of Mississippi, Anne Piazza
Honors Theses
Student anxiety, specifically test anxiety, is common hindrance to student performance in various courses including Human Anatomy and Physiology at the University of Mississippi. Through a sequence of three surveys we collected demographic information, anxiety data related to the course, and test anxiety in general We researched factors that could potentially influence student anxiety such as at what point in the semester the student is evaluated, when students feel the most stressed, outcomes on previous evaluations, and perceived outcomes of the course. We also examined what effect the anxiety has on the student such as lowered performance, lowered test scores, …
Ameliorative Effects Of Minor Cannabinoids Over Hiv-1 Tat-Mediated Visceral Pain, Charlie Worth
Ameliorative Effects Of Minor Cannabinoids Over Hiv-1 Tat-Mediated Visceral Pain, Charlie Worth
Honors Theses
As the total number of people living with HIV continues to rise across the world, an effective HIV treatment is still sought after. While modern-day advanced therapies exist for mitigating much of the negative effects of HIV, the virus remains evasive and problematic in the central nervous system. Thus, even with treatment, many people living with HIV continue to suffer from a plethora of symptoms. However, a large proportion of HIV-positive patients claim to feel a reduction in those persevering symptoms after cannabis usage. This anecdotal evidence has sparked interest in the efficacy of cannabis constituents for HIV therapy. This …