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Full-Text Articles in Medicine and Health Sciences
Prognostic Value Of Patient-Reported Symptom Interference In Patients With Late-Stage Lung Cancer, Bradley J. Barney, Xin Shelley Wang, Charles Lu, Zhongxing Liao, Valen E. Johnson, Charles S. Cleeland, Tito R. Mendoza
Prognostic Value Of Patient-Reported Symptom Interference In Patients With Late-Stage Lung Cancer, Bradley J. Barney, Xin Shelley Wang, Charles Lu, Zhongxing Liao, Valen E. Johnson, Charles S. Cleeland, Tito R. Mendoza
Faculty and Research Publications
Purpose
Patient-reported outcomes (PROs) have been found to be significant predictors of clinical outcomes such as overall survival (OS), but the effect of demographic and clinical factors on the prognostic ability of PROs is less understood. Several PROs derived from the 12-item Short-Form Health Survey (SF-12) and M. D. Anderson Symptom Inventory (MDASI) were investigated for association with OS, with adjustments for other factors, including performance status.
Methods
A retrospective analysis was performed on data from 90 patients with stage IV non-small cell lung cancer. Several baseline PROs were added to a base Cox proportional hazards model to examine the …